Pharmacognosy and Phytochemistry-II
Teacher
ABHISEK SAHU
Category
Core Courses
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Course Name : Pharmacognosy & Phytochemistry
Code(Credit) : BPHT3104(4-0-0)
Course Objectives:
The main purpose of subject is to impart the students the knowledge of how the secondary metabolites are produced in the crude drugs, how to isolate and identify and produce them industrially. Also this subject involves the study of producing the plants and phytochemicals through plant tissue culture, drug interactions and basic principles of traditional system of medicine.
Course Outcomes
| CO | Statement | Mapping with POs |
| CO-1 | To know the modern extraction techniques, characterization and identification of the herbal drugs and phytoconstituents. | PO1, PO2, PO8 |
| CO-2 | To understand the preparation and development of herbal formulation. | PO1, PO6, PO9 |
| CO-3 | To understand the herbal drug interaction. | PO1, PO2, PO8 |
| CO-4 | To carryout isolation and identification of phytoconstituents. | PO1, PO3, PO6, PO8 |
| CO-5 | To get professional, practical skills in extraction isolation and phytochemical analysis of natural products. | PO1, PO2, PO6 |
Course Syllabus
Module-I
Metabolic pathways in higher plants and their determination
a) Brief study of basic metabolic pathways and formation of different secondary metabolites
through these pathways- Shikimic acid pathway, Acetate pathways and Amino acid pathway.
b) Study of utilization of radioactive isotopes in the investigation of Biogenetic studies.
Module II
General introduction, composition, chemistry & chemical classes, biosources, therapeutic
uses and commercial applications of following
secondary metabolites:
Alkaloids: Vinca, Rauwolfia, Belladonna, Opium,
Phenylpropanoids and Flavonoids: Lignans, Tea, Ruta
Steroids, Cardiac Glycosides & Triterpenoids: Liquorice, Dioscorea, Digitalis
Volatile oils: Mentha, Clove, Cinnamon, Fennel, Coriander,
Tannins: Catechu, Pterocarpus
Resins: Benzoin, Guggul, Ginger, Asafoetida, Myrrh, Colophony
Glycosides: Senna, Aloes, Bitter Almond
Iridoids, Other terpenoids & Naphthaquinones: Gentian, Artemisia, taxus, carotenoids
Module III
Isolation, Identification and Analysis of Phytoconstituents
a) Terpenoids: Menthol, Citral, Artemisin
b) Glycosides: Glycyrhetinic acid & Rutin
c) Alkaloids: Atropine,Quinine,Reserpine,Caffeine
d) Resins: Podophyllotoxin, Curcumin
Module IV
Industrial production, estimation and utilization of the following phytoconstituents:
Forskolin, Sennoside, Artemisinin, Diosgenin, Digoxin, Atropine, Podophyllotoxin, Caffeine,
Taxol, Vincristine and Vinblastine
Module V
Basics of Phytochemistry
Modern methods of extraction, application of latest techniques like Spectroscopy,
chromatography and electrophoresis in the isolation, purification and identification of crude
drugs.
References:
1. W.C.Evans, Trease and Evans Pharmacognosy, 16th edition, W.B. Sounders & Co.,
London, 2009.
2. Mohammad Ali. Pharmacognosy and Phytochemistry, CBS Publishers &
Distribution, New Delhi.
3. Text book of Pharmacognosy by C.K. Kokate, Purohit, Gokhlae (2007), 37th Edition,
Nirali Prakashan, New Delhi.
4. Herbal drug industry by R.D. Choudhary (1996), Ist Edn, Eastern Publisher, New
Delhi.
5. Essentials of Pharmacognosy, Dr.SH.Ansari, IInd edition, Birla publications, New
Delhi, 2007
6. Herbal Cosmetics by H.Pande, Asia Pacific Business press, Inc, New Delhi.
7. A.N. Kalia, Textbook of Industrial Pharmacognosy, CBS Publishers, New Delhi,
2005.
8. R Endress, Plant cell Biotechnology, Springer-Verlag, Berlin, 1994.
9. Pharmacognosy & Pharmacobiotechnology. James Bobbers, Marilyn KS, VE Tylor.
10. The formulation and preparation of cosmetic, fragrances and flavours.
11. Remington’s Pharmaceutical sciences.
12. Text Book of Biotechnology by Vyas and Dixit.
13. Text Book of Biotechnology by R.C. Dubey.
Session 8
Study of utilization of radioactive isotopes in the investigation of Biogenetic studies.
Session 9
Study of utilization of radioactive isotopes in the investigation of Biogenetic studies.
Session 10
General introduction, composition, chemistry & chemical classes, biosources, therapeutic uses and commercial applications of Alkaloids: Vinca, Belladonna,
Session 12
Phenylpropanoids and Flavonoids: Lignans, Tea, Ruta
Session 14
Session 27
Isolation, Identification and Analysis of Phytoconstituents
a) Terpenoids: Menthol, Citral, Artemisin
Session 28
Isolation, Identification and Analysis of Phytoconstituents Glycosides: Glycyrhetinic acid & Rutin
Session 29
Isolation, Identification and Analysis of Phytoconstituents
https://www.youtube.com/watch?v=sSO6fLO7_UA
Alkaloids: Atropine,Quinine,Reserpine,Caffeine
Session 30
Isolation, Identification and Analysis of Phytoconstituents
Resins: Podophyllotoxin, Curcumin
Session 31
Industrial production, estimation and utilization of the following phytoconstituents:
Sennoside
Session
Session 32
Industrial production, estimation and utilization of the following phytoconstituents:Forskolin
https://www.youtube.com/watch?v=eoWtqAqdsTU
Session 33
Industrial production, estimation and utilization of the following phytoconstituents: Caffeine
Session 34
Industrial production, estimation and utilization of the following phytoconstituents: Vincristine and Vinblastine
Session 35
Industrial production, estimation and utilization of the following phytoconstituents: Taxol,
Session 36
Industrial production, estimation and utilization of the following phytoconstituents:Digoxin
Session 37
Industrial production, estimation and utilization of the following phytoconstituents : Diosgenin
Session 38
Industrial production, estimation and utilization of the following phytoconstituents: Artemisinin,
Session
Session
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