BASIC & OCULAR PHARMACOLOGY CUTM 1798

Teacher

Syamala Alana Teja

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COURSE OBJECTIVES :

This course covers the actions, uses, adverse effects and mode of administration of
drugs, especially related to eyes.

COURSE OUTCOMES:

At the end of the course the students will acquire knowledge in the following aspects-
1. Basic principle of pharmacokinetics & Pharmacodynamics
2. Commonly used ocular drugs, mechanism, indications, contraindications, drug dosage and
adverse effects.

COURSE SYLLABUS :

Module-1(8 hours)
Pharmacokinetics: Drug absorption, distribution, metabolism and excretion;

Module-2 (8 hours): Pharmacodynamics: Drug Handling by the body; effect of drug and the
relationship between drug concentration and response; Drug – Receptor interactions;
Module-3 (8hrs)
Ocular Pharmacology: Drug Handling by cells and Tissues;Pharmacokinetics and
Pharmacodynamics;specific to ocular – surface and intraocular conditions;
Module-4 (6hrs)
Delivery methods of Ocular Medication; Residence in the conjunctival sac; drug vehicles affect
drug delivery; advanced ocular delivery systems;Reconstituting the tear film: Tear Substitutes;
Module-5 (6hrs)
Ocular Drugs and the Autonomic Nervous system; Parasympathetic(anti muscaranic); and
Sympathetic;

Module-6(6hrs)
Intraocular pressure Drugs(Anti Glaucoma Drugs); Eicosanoids: prostaglandins; thromboxanes
and leukotrienes;
Serotonin;
Module: 7 (6hrs)
Neurotransmitter; Glucocorticoids, Immunosuppressive agents; Local Anesthetics; Ocular
Toxicity from systemic administration of Drugs supervised setting;

Projects:
Pharmacokinetics of Drugs
Pharmacodynamics of Drugs
Drug receptor interactions
Different types of delivery methods of ocular medications
ocular drugs and its effects on parasympathetic nervous system
ocular drugs and its effects on sympathetic nervous system
Drugs used for IOP

Text Books

1) K D TRIPATHI : Essentials of Medical Pharmacology. 4 th Ed.,2003
2) T S MAUGER & E L CRAIG - MOSBY'S - OCULAR DRUG HANDBOOK
3) BUTTERWORTH AND HEINMANN - Clinical Ocular Pharmacology 5th

Edition.
Reference Book:

1) Zimmerman: Text Book of Ocular
Pharmacology,1999
2) Bartlett and Jaanus: Clinical Ocular
Pharmacology

S P RANG , M M DALE, RITTER – Pharmacology, Ed.3 Churchill 1995.

SESSION 1

Pharmacokinetics:Absorption

Presentation

PHARMACOKINETICS ABSORPTION AND DISTRIBUTION

https://www.youtube.com/watch?v=8-Qtd6RhfVAhttps://www.slideshare.net/pooranachithraflowry/introduction-to-pharmacokinetics-and-pharmacodynamics-principleshttps://www.youtube.com/watch?v=pWW-aq7iSa0https://www.slideshare.net/animeshgupta583/drug-absorption

SESSION 2

Pharmacokinetics:Distribution

Presentation :

PHARMACOKINETICS ABSORPTION AND DISTRIBUTION

Drug distribution

https://www.youtube.com/watch?v=6erefsWCVxg

https://www.slideshare.net/UmasankarKrishnamaraju/drug-distribution-40685564

SESSION 3

Pharmacokinetics:Metabolism

Presentation

PHARMACOKINETICS ABSORPTION AND DISTRIBUTION

Drug metabolism

https://www.youtube.com/watch?v=oCPRi5JFMdg

https://www.slideshare.net/swaroophassan/drug-metabolism-40740005

SESSION 4

Pharmacokinetics:Excretion

Presentation PHARMACOKINETICS ABSORPTION AND DISTRIBUTION

Drug excretion

https://www.youtube.com/watch?v=VZRVt9r4oSM

https://www.slideshare.net/sarita1916/drug-excretion-72976060

https://www.slideshare.net/girijeshpandey180/drug-elimination-238374041

SESSION 5

Pharmacodynamics and introduction

drug receptor interactions

presentation

Pharmacodynamics-1

Drug – Receptor interactions

https://www.youtube.com/watch?v=YonbZHGYMt4

https://www.slideshare.net/siddharthadutta8/receptor-pharmacology-types-and-drug-receptor-interactions

SESSION 6

Pharmacodynamics -Drug handling by the body

Presentation

Pharmacodynamics-1

Pharmacodynamics: Drug Handling by the body – effect of drug and the relationship between drug concentration and response

https://www.youtube.com/watch?v=VzrvklX5Wmw

https://www.slideshare.net/saurabhwani77/dose-response-relationship

SESSION 7

Pharmacodynamics -Drug handling by the body

Presentation

Pharmacodynamics-1

Pharmacodynamics: Drug Handling by the body – effect of drug and the relationship between drug concentration and response

https://www.youtube.com/watch?v=VzrvklX5Wmw

https://www.slideshare.net/saurabhwani77/dose-response-relationship

SESSION 8

Pharmacodynamics -Effect of drug and relationship between drug concentration and response

Presentation

Pharmacodynamics-1

PharmaCodynamic-2

SESSION 9

Pharmacodynamics -Effect of drug and relationship between drug concentration and response

Presentation

Pharmacodynamics-1

PharmaCodynamic-2

SESSION 10

Pharmacodynamics -Effect of drug and relationship between drug concentration and response

Presentation

Pharmacodynamics-1

PharmaCodynamic-2

SESSION 11

Pharmacodynamics -Effect of drug and relationship between drug concentration and response

Presentation

Pharmacodynamics-1

PharmaCodynamic-2

SESSION 12

Ocular pharmacology introduction

Presentation

https://www.slideshare.net/laxmieyeinstitute/ocular-pharmacology-60484596

SESSION 13

Ocular pharmacology introduction

Presentation

Video:

http://courseware.cutm.ac.in/wp-content/uploads/2023/07/PHARMACOKINETICS-ABSORPTION-AND-DISTRIBUTION.pptx

Ocular Pharmacology: Drug Handling by cells and Tissues – Pharmacokinetics, and Pharmacodynamics– specific to ocular – surface and intraocular conditions

https://www.youtube.com/watch?v=mhXvLfsLgrQ

https://www.youtube.com/watch?v=guspTGxUO_c

https://www.slideshare.net/guest86523812/ocular-pharmacology

https://www.slideshare.net/osaidtaisir7/ocular-pharmacokinetics-81399267

https://www.slideshare.net/DrVishalPawar/ocular-pharmacology-105610058

SESSION 14

Ocular pharmacology Pharmacokinetics and Pharmacodynamics-specific to ocular surface

presentation

https://www.slideshare.net/laxmieyeinstitute/ocular-pharmacology-60484596

SESSION 15

Ocular pharmacology Pharmacokinetics and Pharmacodynamics-specific to ocular surface

presentation

https://www.slideshare.net/laxmieyeinstitute/ocular-pharmacology-60484596

SESSION 16

Delivery methods of ocular Medications

presentation slideshare