Course Objectives

• Determine the parts of the cell membrane and the cell wall
• Distinguish the types and mechanism of mutation
• Compare and contrast the events of cell cycle and its regulation
• Understand the dynamic character of cellular organelles

Learning Outcomes

• Describe the fundamental principals cellular biology
• Develop a deeper understanding of cell structure and how it relates to cell functions.
• Understand how cells grow, divide, and die and how these important processes are regulated.
• Understand cell signaling and how it regulates cellular functions. Also how its dis-regulation leads to cancer and other diseases.

Course Syllabus

Module –I ( 12 Hr)
An Overview of Cells: History, Cell theory, Structure and Function of Cell and its Organelles: Biological membranes - Nucleus - Nuclear envelope, Nucleolus, Mitochondria, Chloroplasts, Lysosomes, Gloxysomes and Peroxisomes, endoplasmic reticulum, ribosomes, Golgi complex (Structural organization, function, marker enzymes of the above organelles), Cell types: prokaryotes vs. eukaryotes; from single cell to multi-cellular organism; Different molecules of cell- water, salt and mineral ions etc.

Module –II (14 H r)
Cell cycle and its regulation, Cellular communication and cell mobility: Cell cycle: G0/G1, S, G2 and M phages (Cell Division: Mitosis, meiosis and cytokinesis); regulation of cell cycle; cell adhesion and roles of different adhesion molecules, gap junctions, Extra- Cellular Matrix (ECM), Cell-cell interaction and cell- ECM interaction, The cytoskeleton, Microtubule- based movement and microfilament -based movement.
Module –III (14 Hr)
Cell signaling, Programmed Cell Death (Apoptosis) and Cancer: Hormones and their receptors, cell surface receptor, signaling through G-protein coupled receptors (G-PCR), Tyrosine Kinase, signal transduction pathways, second messengers, regulation of signaling pathways, bacterial and plant two-component systems, bacterial chemotaxis, Intrinsic and Extrinsic apoptotic pathway, Caspase enzyme, Biology and elementary knowledge of development and causes of cancer; Tumor viruses, Oncogenes and tumor suppressor genes,

Session Plan

Session 1

Topic -Defination and History of Cell
Refer Book - Cell Biology (7th Edition ) by Karp G, John Wiley Page no. 02
The Cell a Molecular Approach (4th Edition ) by Cooper & Hausman. Page no.4-15
Video - https://youtu.be/4OpBylwH9DU
https://youtu.be/LFyjJBiltFI

Presentation - https://www.slideshare.net/RaihaBilal/introduction-cell
https://www.slideshare.net/earshadshinichi/cell-biology-the-cell-its-structure-and-history

Session 2

Topic - Cell theory
Video- https://youtu.be/vqY-PvUKm8Q
https://youtu.be/zk3vlhz1b6k
Presentation - https://www.slideshare.net/prakashtu/cell-and-cell-theory
https://www.slideshare.net/maryanntiam/cell-theory-179362681

Session 3

Topic - Structure and Function of Cell and its Organelles
Refer Book - The Cell a Molecular Approach (4th Edition ) by Cooper & Hausman. Page no.353
Video - https://youtu.be/V6s0xOTNmT4
https://youtu.be/Hmwvj9X4GNY
Presentation - https://www.slideshare.net/pugazhkurianc/cell-structure-and-function-10144056
https://www.slideshare.net/wthompsonctems/keynote-ch-3-cell-structure-function

Session 4

Topic - Biological membranes
Refer Book -The Cell a Molecular Approach (4th Edition ) by Cooper & Hausman. Page no 58
Video - https://youtu.be/uhZ_ALt51TM
Presentation - https://www.slideshare.net/PradeepNarwat/biological-membrane-its-chemical-composition

Session 5

Topic - Nucleus
Refer Book - The Cell a Molecular Approach (4th Edition ) by Cooper & Hausman. Page no 355
Video - https://youtu.be/gGeC0ntvxR8
https://youtu.be/EmlJOvDawXI
Presentation - https://www.slideshare.net/saritananda/nucleus-81376601
https://www.slideshare.net/akshaygmore27/nucleus-54263255

Session 6

Topic - Nuclear envelope
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no 356
Video - https://youtu.be/tQyeSpLlSGg
https://youtu.be/Vkz-JZVXq7o

Session 7

Topic - Nucleolus
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no 375
Video - https://youtu.be/HobSglXNtYk
https://youtu.be/kAKPiVb7nYU

Session 8

Topic - Mitochondria
Refer Book - Cell Biology (7th Edition ) by Karp G, John Wiley page no. 179
The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no .434
Video - https://youtu.be/CVs4WLdQDco
https://youtu.be/39HTpUG1MwQ
Presentation - https://www.slideshare.net/devadevi666/mitochondria-ppt

Session 9

Topic - Chloroplasts
Refer Book - Cell Biology (7th Edition ) by Karp G, John Wiley page no- 213
The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no .451
Video - https://youtu.be/uewfzOH-Vu4
Presentation - https://www.slideshare.net/kaushal2683/chloroplast-by-kk-sahu-sir

Session 10

Topic - Lysosomes
Refer Book - Cell Biology (7th Edition ) by Karp G, John Wiley page no- 303
The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.424
Video - https://youtu.be/TDRtEszzs78
https://youtu.be/02jrzh9m92M
Presentation - https://www.slideshare.net/squid923/lysosome-powerpoint

Session 11

Topic - Gloxysomes and Peroxisomes
Refer Book - Cell Biology (7th Edition ) by Karp G, John Wiley page no- 206
The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no 462
Video - https://www.slideshare.net/Dilippandya/peroxisome-46636423

Session 12

Topic - Endoplasmic reticulum
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.386
Video - https://youtu.be/QO4WwyVt3cU
Presentation - https://www.slideshare.net/AshishNain/endoplasmic-reticulum-cell-organelle

Session 13

Topic - Golgi complex (Structural organization function, marker enzymes of the above organelles)

Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no. 408

Video - https://youtu.be/CfnH1BT-NjE
Presentation - https://www.slideshare.net/tukaramgitte/golgi-complex-160381391

Session 14

Topic - Cell types: prokaryotes vs. eukaryotes
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.529
Video - https://youtu.be/xTnNv7YplSo
Presentation - https://www.slideshare.net/CandelaContent/lab-2-microbiology
https://www.slideshare.net/gkumarimahesh/prokaryotic-and-eukaryotic-algal-cell-structure

Topic - From single cell to multi-cellular organism
Video - https://youtu.be/-BobUiQRhJ0

Session 15

Session 20

Topic - Cell cycle and its regulation
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.599
Video - https://youtu.be/gTZ_vj-HdzM
Presentation - https://www.slideshare.net/abishadh/cell-cycle-in-relation-to-cancer

Session 21

Topic - Cellular communication and cell mobility
Video - https://youtu.be/QYv_n7tGfro

Session 22

Topic - Cell cycle: G0/G1, S, G2 and M phages
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no. 649
Video - https://youtu.be/PQhQ80UGwBo
Presentation - https://www.slideshare.net/abishadh/cell-cycle-in-relation-to-cancer

Session 23

Topic - Cell Division: Mitosis, meiosis and cytokinesis
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no. 649
Video - https://youtu.be/6ojLPvt90aI
https://youtu.be/QbdFcQSF_tY

Session 24

Topic - Regulation of cell cycle
Video - https://youtu.be/hSTeawTvoIU

Session 25

Topic - Cell adhesion and roles of different adhesion molecules
Video - https://youtu.be/vnWMlcN8Kz0
https://youtu.be/FhiWfEVj5yY
Presentation - https://www.slideshare.net/AllergyChula/cellular-adhesion-molecules

Session 26

Topic - Gap junctions
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.589

Video - https://youtu.be/attLYnvWH9M
https://youtu.be/K3UMcOmn6z4
Presentation -

https://www.slideshare.net/MrithulKBenny2/tight-junctiongap-junctionand-desmosomes

Session 27

Topic -Extra- Cellular Matrix (ECM)
Refer Book -The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no 575
Video - https://youtu.be/WBZUDd5sPWc
Presentation - https://www.slideshare.net/AdarshPP2/extra-cellular-matrix-191829107

Session 28

Topic - Cell-cell interaction and cell- ECM interaction
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no 584
Video - https://youtu.be/AB3xzPcWWKg

Session 29

Topic - The cytoskeleton
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no 473
Video - https://youtu.be/hxsFWg6uPLs
Presentation - https://www.slideshare.net/MariyaRaju/the-cytoskeleton-76803043

Session 30

Microtubule-based movement and microfilament-based movement
The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.505

https://www.coursera.org/lecture/advanced-neurobiology1/3-1-3-organelles-and-cytoskeleton-in-neurons-y8asq
www.powershow.com/...Movement_powerpoint_ppt_presentation
http://biologydictionary.net/microfilament

Session 31

Cell signaling
The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no 599
https://www.coursera.org/lecture/advanced-neurobiology1/3-1-3-organelles-and-cytoskeleton-in-neurons-y8asq
www.authorstream.com/.../shona6685-645587-ppt-cell-signaling

Session 32

Topic - Programmed Cell Death (Apoptosis) and Cancer
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.689-690
Video - https://youtu.be/wkWLmlSUlqg
https://youtu.be/Ft-2LCqmdQY
Presentation - https://www.slideshare.net/Mahmoud-Shab/cell-apoptosis-programmed-cell-death

Session 33

Topic - Hormones and their receptors
Video - https://youtu.be/a5A47SZfuIY

Session 34

Topic - Cell surface receptor
Refer Book - The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.609
Video - https://youtu.be/zLhwoSjNzk0
https://youtu.be/i7_VTkhR3UI

Session 35

Signaling through G-protein coupled receptors (G-PCR)
The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.610
https://www.coursera.org/lecture/systems-biology/molecules-to-pathways-camp-and-g-protein-pathways-ii-zRk67

Session 36

Tyrosine Kinase
The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.612-616
https://www.coursera.org/lecture/energy-metabolism/3-actions-of-insulin-rKlLm
http://www.slideshare.net/charan358/tyrosine-kinase-ppt
www.authorstream.com/...tyrosine-kinase-cell-signaling-ppt

Session 36

Signal transduction pathways
The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.637
https://www.coursera.org/lecture/advanced-neurobiology1/3-2-6-crosstalk-of-cellular-signal-transduction-pathways-RXf6j
www.scribd.com/.../182159741/Signal-Transduction-ppt
www.slideshare.net/manishpharma/signal...

Session 37

Second messengers
The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.618
https://www.coursera.org/lecture/advancedneurobiologyii/1-1-10-second-messengers-qaMH7
www.slideshare.net/.../second-messenger-systems
www.xpowerpoint.com/ppt/second-messenger.html

Session 38

Regulation of signaling pathways
https://www.coursera.org/lecture/advanced-neurobiology1/3-2-7-the-ltp-oqpA5
www.slideshare.net/Raghusolanki001/introduction...

Session 39

Bacterial and plant two component systems
https://www.intechopen.com/books/protein-phosphorylation-in-human-health/bacterial-two-component-systems-structures-and-signaling-mechanism
www.caister.com/.../twocomponentsystems/index.html

Session 40

Bacterial chemotaxis
https://www.ks.uiuc.edu/Research/chemotaxis/
http://www.slideshare.net/THANKLORD/chemotaxis-33135684

Session 41

Intrinsic and Extrinsic apoptotic pathway
https://www.coursera.org/lecture/extracellular-vesicles-health-disease/lecture-2-7-apoptotic-senescence-physiological-processes-BpLbJ
http://www.slideshare.net/saquibkhan5/apoptosis-28305415

Session 42

Caspase enzyme
The Cell a Molecular Approach (4th Edition) by Cooper &
Hausman. Page no.692
https://www.sigmaaldrich.com/life-science/cell-biology/cell-biology-products.html?TablePage=9564314
http://www.slideshare.net/vishakha_99/apoptosisppt-48787715

Session 43

Biology and elementary knowledge of development and causes of cancer
https://www.udemy.com/course/cancer-biology-101/

Session 44

Tumor viruses, Oncogenes and tumor suppressor genes,
The Cell a Molecular Approach (4th Edition) by Cooper & Hausman. Page no.729
https://www.udemy.com/course/anecdotes-in-cancer-biology/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944361/

Case Studies

Case Studies