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COURSE OBJECTIVE
This course serves as an introduction to the basic principles of forensic pharmacology. Students will learn key concepts that are important to understanding drug actions, including principles of pharmacokinetics (e.g., absorption, distribution, metabolism and excretion of drugs) as well as the physiological and cellular basis for a host of diverse drug actions.
COURSE OUTCOME
| SNO | DESCRIPTION | PO MAPPING |
| CO1 | Understand about the drug, factors, bioavailability, and responses of drugs. | PO6, PO9, PO12 |
| CO2 | Understanding the different agents of drugs, designer drugs and NDPS substances. | PO6, PO9, PO12, PO15 |
| CO3 | Analysis of drugs and agents. | PO6, PO9, PO12,PO15 |
| CO4 | Qualitative and quantitative analysis of various chemicals. | PO6, PO9, PO12, PO15 |
| CO5 | Instrumental analysis of various chemicals. | PO6, PO9, PO12, PO15 |
UNIT- I Basic Principles of Pharmacology
Introduction to Pharmacology
Pharmacopoeias IP, USP, EP
Drug & Drug Receptor mechanisms
Pharmacodynamics
Factor affecting the effects of Drug
Post mortem redistribution
UNIT- II Pharmacokinetics
L-ADME
Bioavailability and Bioaccumulation
Dose response relationship
Drug Interactions like Agonism, Antagonism, Addition, Synergism, Potentiation
Adverse drug reactions and pharmacogenetics
Drug concentration and pharmacological response
Drug dependence and drug abuse
UNIT- III Pharmacology and Pharmaceutical Analysis
Aliphatic alcohols
General and local Anesthetics
CNS Stimulants
Sedative, Hypnotics and Pharmacotherapy of sleep disorders
Drugs effective in convulsive disorders
UNIT- IV Pharmacology and Pharmaceutical Analysis
Antipsychotic Agents
Antidepressant drugs
Antiseizure Drugs
Drugs of Abuse
Tranquillizers
Narcotic Drugs and Psychotropic Substance
Schedule and Nonscheduled Drugs
Designer Drugs
Doping Drugs
Hallucinogens
UNIT- V Pharmacology and Pharmaceutical Analysis
Chemotherapeutic Drugs
Antibacterial
Antifungal agents
Antiviral agents
Antiprotozoal Drugs
Disinfectants, Antiseptics and Sterilants
REFERENCE BOOKS
Klaassen, C. D.,:Casarett and Doull’s Toxicology: The Basic Sciences of Poisons, 5th ed, McGraw-Hill, 1995.
Moffat, A.C. : Osselton, D. M. Widdop, B. : Clarke’s Analysis of Drugs and Poisons in Pharmaceuticals, body fluids and postmortem material, 3rd ed., Pharmaceutical Press2004.
Bogusz, M. J.,: Hand Book of Analytical Separations, Vol. 2: Forensic Sciences, 1st ed., Elsevier Sciences ,2000.
Siegel, J.A., Saukko, P. J., Knupfer, G.,: Encyclopedia of Forensic Sciencess (Vol3), Academic Press, 2000.
Rang, P.H., Dale, M.M., Ritter, M.J.: Pharmacology, 4th ed., Harcourt/Churchill Livingstone, 2000.
Paranjape, H.M., Bothara, G.K., Jain, M.M.: Fundamentals of Pharmacology, 1st ed., Nirali Prakashan, 1990.
Session 1
Introduction to Pharmacology, Pharmacopoeias IP, USP, EP
Session 3
Factor affecting the effects of Drug, Post mortem redistribution
Session 7
Dose response relationship
Drug Interactions like Agonism, Antagonism, Addition, Synergism, Potentiation
Session 9
Drug concentration and pharmacological response
Drug dependence and drug abuse
Session 10
Aliphatic alcohols
Session 13
Sedative, Hypnotics and Pharmacotherapy of sleep disorders
Session 18
Drugs of Abuse
Session 21
Schedule and Nonscheduled Drugs
Session 25
Chemotherapeutic Drugs
pharmd_3Y_3.1_pharmacology.pdf
https://www.uio.no/studier/emner/matnat/kjemi/KJM5230/h08/undervisningsmateriale/Kap39-41.pdf
Session 29
Disinfectants, Antiseptics and Sterilants