FORENSIC TOXICOLOGY (CUTM2318)

Course Name: Forensic Toxicology

Code(Credit): CUTM2318 (3+2+0)

Course Objectives

• Concepts of poison and toxic materials.
• Understanding of toxic agents and their risk assessments

Course Outcomes

• Gain knowledge on different toxic substances and their identification and
  detection.
• Gain skills in demonstrating the analytical methods of toxicology and its
  application
• Ability to detect the poison by various analytical techniques from biological
  and non-biological matrices

Syllabus

Unit 1: Basics of Toxicology
Introduction to toxicology, different branches of toxicology, concepts of forensic toxicology. Scope and application forensic toxicology. Significance of toxicological findings. Techniques used in toxicology. Toxicological analysis and chemical intoxication tests. Post-mortem Toxicology. Human performance toxicology. Dose-response relationship. Lethal dose 50 and effective dose 50.

Unit 2: Collection & Preservation of Toxicological Evidences

Collection and preservation of viscera, blood and urine for various poison cases.

Unit 3: Plant Poison
Classification, Fatal Dose, fatal Period, Sign & symptoms, Post-mortem Appearance, Medico legal
Importance, Treatment & Analysis- Screening & Instrumental.

Unit 4: Animal Poison
Classification, Fatal Dose, fatal Period, Sign & symptoms, Post-mortem Appearance, Medico legal
Importance, Treatment & Analysis- Screening & Instrumental.

Unit 5: Metallic Poisons

Classification, Fatal Dose, fatal Period, Sign & symptoms, Post-mortem Appearance, Medico legal
Importance, Treatment & Analysis- Screening & Instrumental.

Unit 6: Acidic & Alkali poisons
Classification, Fatal Dose, fatal Period, Sign & symptoms, Post-mortem Appearance, Medico legal
Importance, Treatment & Analysis- Screening & Instrumental.

Unit 7: Neutral Poisons
Classification, Fatal Dose, fatal Period, Sign & symptoms, Post-mortem Appearance, Medico legal
Importance, Treatment & Analysis- Screening & Instrumental

Subjects Readings

1. R. Saferstein, Criminalistics, 8th Edition, Prentice Hall, New Jersey (2004).
2. F.G. Hofmann, A Handbook on Drug and Alcohol Abuse, 2nd Edition, Oxford University
   Press, New York (1983).
3. S.B. Karch, The Pathology of Drug Abuse, CRC Press, Boca Raton (1996).
   A. Poklis, Forensic toxicology in, Introduction to Forensic Sciences, 2nd Edition, W.G. Eckert
   (Ed.), CRC Press, Boca Raton (1997).
4. A.W. Jones, Enforcement of drink-driving laws by use of per se legal alcohol limits: Blood
   and/or breath concentration as evidence of impairment, Alcohol, Drug and Driving, 4, 99
   (1988).
5. W.J. Tilstone, M.L. Hastrup and C. Hald, Fisher’s, Techniques of Crime Scene Investigation,
   CRC Press, Boca Raton (2013).

Practical's

1. Perform the colour test for the given acidic drug/poison.
2. Perform the TLC for the given acidic drug/poison.
3. Perform the UV-Visible analysis of drug/poison.
4. Perform the FT-IR analysis of drug/poison.
5. Perform the colour test for the given basic drug/poison.
6. Perform the TLC for the given basic drug/poison.
7. Perform the colour test for the given plant poison.
8. Perform the TLC for the given plant poison.
9. Identify the given metallic poison.
10. Analysis of the given neutral poison

Session Plan

Session 1

Introduction to Toxicology

https://epgp.inflibnet.ac.in/epgpdata/uploads/epgp_content/forensic_science/10._forensic_toxicology/01._introduction_to_forensic_toxicology/et/7459_et_1_et.pdf

Session 2

Postmortem Toxicology

Toxicology_Postmortem

Session 3

Classification of Poisons

https://www.slideshare.net/JayantTiple/classification-of-poisons-and-types-of-poisoningpptx-252803879

Session 4

Plant Poisons

https://anrcatalog.ucanr.edu/pdf/8560.pdf

Session 5

ANIMALPOISONS

Session 6

Metallic Poisons

Forensic_Aspect_of_Metal_Poisoning_A_Review

Session 7

Acid Poisons

https://gmch.gov.in/sites/default/files/documents/corrosive%20poisons.pdf

Session 8

Alkali Poisons

https://www.slideshare.net/ammarabatool2/acids-and-alkalis-f

Session 9

Neutral Poisons

https://www.slideshare.net/raghurx/poisons-105662036