Fundamentals of Genetics
Teacher
Dr. Praveen Kumar
Category
Core Courses
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Course Name : FUNDAMENTALS OF GENETICS
Code(Credit) : ASPG1101(2-1-0)
Course Objective
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To impart knowledge to the students on the ultrastructure of cell and cell organelles
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To equip students in both conventional and modern principles of genetics
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Applications of principles of genetics in plant breeding for improving agricultural productivity
CO-PO Mapping
COs |
Course outcomes |
Mapping COs with POs |
CO1 |
Students will be able to understand the basic concepts of the ultrastructure of cell, cell organelles, chromosomes and nucleic acids. |
PO1 |
CO2 |
Students could gain acquaintance with the fundamentals of chromosomal and cytoplasmic inheritance. |
PO2 |
CO3 |
Students will be able to understanding on sex determination, mutations, chromosomal aberrations and Gene concept: Gene structure, function and regulation |
PO1 |
CO4 |
Students will be able to apply the principles of inheritance to plant breeding.
|
PO4 |
PO1: Knowledge Enhancement
PO2: Professional Enhancement
PO3: Entrepreneurship Skills
PO4: Communication & Extension Skill
Programme Outcomes
PO1 : Knowledge Enhancement : Demonstrate knowledge and understanding of essential facts, concepts, principles and theories relating to Soil Science, Agronomy, Horticulture, Genetics and Plant Breeding, Plant Pathology, Entomology and other such areas of agriculture.
PO2 : Professional Enhancement : Understanding the value and processes of life-long learning and professional development.
PO3 : Entrepreneurship Skills : Understanding the processes of setting up and managing viable business ventures.
PO4 : Communication & Extension Skills : Developing appropriate communication skills for effective transfer of knowledge and technologies through extension programs.
PO5 : Team Work : Play effective roles in multidisciplinary teams.
PO6 : Educational Leadership : Recognize and meet emerging agriculture challenges of global society in the 21st century and developing leadership and strong linkages in the agro-industrial setup.
PO7 : Data Handling : Collect, analyze and interpret scientific data.
PO8 : Ethics : Apply ethical principles and commit to professional ethics and responsibilities and norms of the scientific practice.
PO9 : Computational Skills : Recognize, analyze problems and plan strategies for their solutions with the help of computer skills.
Course Syllabus
Theory
Pre and Post Mendelian concepts of heredity, Mendelian principles of heredity, Cell division – mitosis, meiosis, Probability and Chi-square.Dominance relationships, gene interaction.
Multiple alleles, pleiotropism and pseudoalleles, Sex determination and sex linkage, sex limited and sex influenced traits, Blood group genetics, Linkage and its estimation, crossing over mechanisms, chromosome mapping. Structural changes in chromosome, Mutation, classification, Methods of inducing mutation & CIB technique, mutagenic agents and induction of mutation. Qualitative & Quantitative traits, Polygenes and continuous variations, multiple factor hypothesis, Epistatic interactions with examples. Cytoplasmic inheritance. Genetic disorders,.Nature, structure & replication of genetic material. Protein synthesis, Transcription and translational mechanism of genetic material, Gene concept: Gene structure, function and regulation, Lac and Trp operons.
Practical
Study of microscope.Study of cell structure. Experiments on monohybrid, dihybrid, trihybrid, test cross and back cross, Experiments on epistatic interactions including test cross and back cross, Practice on mitotic and meiotic cell division, Experiments on probability and Chi-square test. Determination of linkage and cross over analysis (through two point test cross and three point test cross data).Study on sex linked inheritance in Drosophila. Study of models on DNA and RNA structure.
References
1. Pundhan Singh, 2006, Genetics, Kalyani Publishers, Ludhiana
2. Singh, B.D. 2015. Fundamentals of Genetics.Kalyani Publishers, Ludhiana
3. Gupta, P.K.2007. Genetics.Rastogi Publications, Meerut
Session 2
Post Mendelian concepts of heredity
Session 4
Mendels Laws of Inheritance
Session 5
Session 7
Qualitative and Quantitative traits
Session 8
Comb Shape in Poultry
Session 10
Multiple alleles
Session 13
Curt Stern Experiment on Crossing Over
Session 15
Chromosome mapping
Chromosome Maps
Session 25
Replication of genetic material and Central Dogma
Replication of DNA and central dogma
Session 27
Structural Chromosomal Aberrations
Session 29
Transcription
Practice-2
Problems on Magnification and Resolving Power
Practice-3
Study of cell Ultrastructure-I (Cell wall, Plasma membrane, Cell wall, Cytoplsam, Endoplasmic Reticulum)
Practice-4
Study of cell Ultrastructure-I (Nucleus, Ribosome, Mitochondria, Lysosome, Chloroplast, Peroxisome)
Practice-5
Experiments on Monohybrid, Dihybrid, Trihybrid crosses
Practice-9
Practice on Meiotic Cell Division
Practice-11
Determination of Linkage and Crossing Over (Estimation of Two-Point test cross)
Practice-12
Determination of Linkage and Crossing Over (Estimation of Three-Point test cross)
| PO1 | PO2 | P03 | P04 | P05 | P06 | P07 | P08 | P09 | |
| CO1 | 3.00 | 3.00 | 3.00 | 2.00 | 2.00 | 1.00 | 2.00 | 2.00 | |
| CO2 | 3.00 | 3.00 | 3.00 | 2.00 | 2.00 | 1.00 | 1.00 | 2.00 | 1.00 |
| CO3 | 3.00 | 3.00 | 3.00 | 2.00 | 2.00 | 2.00 | 1.00 | 2.00 | 2.00 |
| CO4 | 3.00 | 3.00 | 3.00 | 2.00 | 2.00 | 2.00 | 1.00 | 2.00 | 1.00 |
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