Hospital And Clinical Pharmacy




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Course Name : Hospital and Clinical pharmacy

Code(Credit) : DCPY1206(3-2-0)

Course Objectives

  • To be recognised nationally and internationally as a leader in improving medication outcomes and pharmacy practice research and education. To establish relationships with key individuals and organisations to improve the quality use of medicines and health outcomes.

Learning Outcomes

Hospital Pharmacy

Hospital Pharmacy

 1. Know various drug distribution methods

 2. Know the professional practice management skills in hospital pharmacies.

 3. Provide unbiased drug information to the doctors.

Clinical Pharmacy

 1. Interpret evidence and patient data.

 2. Implement and/or recommend patient care plans.

 3. Monitor the patient and adjust the care plan as needed.

Course Syllabus

Module I
Hospital and it’s organization Definition, Classification of hospital- Primary, Secondary and Tertiary hospitals.
Classification based on clinical and non- clinical basis, Organization Structure of a Hospital, and Medical staffs involved in the hospital and their functions.
Hospital pharmacy and its organization Definition, functions of hospital pharmacy Organization structure
Location, Layout and staff requirements, and Responsibilities and functions of hospital pharmacists.
Adverse drug reaction Classifications - Excessive pharmacological effects, secondary pharmacological effects, idiosyncrasy
Allergic drug reactions, genetically determined toxicity, toxicity following sudden withdrawal of drugs
Drug interaction- beneficial interactions, adverse interactions, and pharmacokinetic drug interactions
Methods for detecting 149 drug interactions spontaneous case reports and record linkage studies
Adverse drug reaction reporting and management.
Community Pharmacy Organization and structure of retail and wholesale drug store, types and design
Legal requirements for establishment and maintenance of a drug store, Dispensing of proprietary products
Maintenance of records of retail and wholesale drug store.

Module II
Drug distribution system in a hospital Dispensing of drugs to inpatients, types of drug distribution systems
Charging policy and labelling, Dispensing of drugs to ambulatory patients, and Dispensing of controlled drugs.
Hospital formulary Definition, contents of hospital formulary
Differentiation of hospital formulary and Drug list
Preparation and revision, and addition and deletion of drug from hospital formulary.
Therapeutic drug monitoring Need for Therapeutic Drug Monitoring, Factors to be considered during the Therapeutic Drug Monitoring
Indian scenario for Therapeutic Drug Monitoring.
Medication adherence Causes of medication non-adherence, pharmacist role in the medication adherence, and monitoring of patient medication adherence.
Patient medication history interview Need for the patient medication history interview, medication interview forms.Community pharmacy management Financial, materials, staff, and infrastructure requirements.

Module III
Pharmacy and therapeutic committee Organization, functions, Policies of the pharmacy
Therapeutic committee in including drugs into formulary, inpatient and outpatient prescription, automatic stop order, and emergency drug list preparation.
Drug information services 150 Drug and Poison information centre, Sources of drug information, Computerised services, and storage and retrieval of information.
Patient counseling Definition of patient counseling; steps involved in patient counseling, and Special cases that require the pharmacist
Education and training program in the hospital Role of pharmacist in the education and training program
Internal and external training program, Services to the nursing homes/clinics
Code of ethics for community pharmacy
Role of pharmacist in the interdepartmental communication and community health education.
Prescribed medication order and communication skills Prescribed medication order- interpretation and legal requirements
Communication skills- communication with prescribers and patients.

Module IV

Budget preparation and implementation Budget preparation and implementation
Clinical Pharmacy Introduction to Clinical Pharmacy, Concept of clinical pharmacy.
Functions and responsibilities of clinical pharmacist, Drug therapy monitoring - medication chart review
Clinical review, pharmacist intervention, Ward round participation
Medication history and Pharmaceutical care.
Dosing pattern and drug therapy based on Pharmacokinetic & disease pattern.
Over the counter (OTC) sales Introduction and sale of over the counter, and Rational use of common over the counter medications.

Unit V
Drug store management and inventory control Organisation of drug store, types of materials stocked and storage conditions
Purchase and inventory control: principles, purchase procedure, purchase order, procurement and stocking, Economic order quantity
Reorder quantity level, and Methods used for the analysis of the drug expenditure
Investigational use of drugs 151 Description, principles involved, classification
Investigational use of drugs control, identification, Role of hospital pharmacist, advisory committee. Interpretation of Clinical Laboratory Tests Blood chemistry, hematology, and urinalysis


Books Recommended:(Latest editions)

1. Remington's pharmaceutical sciences.

2.Testing of raw materials used in (1)

3.Evaluation of surgical dressings.

4.Sterilization of surgical instruments, glassware and other hospital supplies.

5.Handling and use of data processing equipments.

Session Plan

Session 1

Hospital-Definition, Function, classifications based on various criteria .

Session 2

Organization and Management health delivery system in India.

Organization of Hospital Pharmacy

Session 3

Hospital Pharmacy: Definition Functions and objectives of Hospital pharmaceutical services.

hospital pharmacy

Session 4

location of hospital pharmaceutical services.

hospital pharmacy

Session 5

layout of hospital pharmaceutical services.

hospital pharmacy

Session 6

Flow chart of materials and men.

hospital pharmacy

Session 7

Personnel and facilities requirements including equipments based on individual and basic needs.

staff, infrastructure, and work load statistics

Session 8

Requirements and abilities required for Hospital pharmacists .

staff, infrastructure, and work load statistics

Session 9

Drug Distribution system in Hospitals.


Session 10

Out-patient service.

Drug Distribution in Hosp Pharmacy

Session 11

In-patient services .

Drug Distribution in Hosp Pharmacy

Session 12

Types of services detailed discussion of unit Dose system .

Central Sterile Supply Unit-converted

Session 13

Floor ward stock system

Drug Distribution in Hosp Pharmacy


Satellite pharmacy services

satellite pharmacy-converted

Session 15

Central sterile services .

Central Sterile Supply Unit-converted

Session 16

Session 17

Manufacturing: Economical considerations, estimation of demand.


Session 18

Sterile manufacture-Large an small volume parenterals .

Central Sterile Supply Unit-converted

Session 19

Facilities for parenterals .

Central Sterile Supply Unit-converted

Session 20

Requirements for parenterals .

Central Sterile Supply Unit-converted

Session 21

Layout production planning .

Drug distribution methods

Session 22

Session 23

Non-sterile manufacture-Liquid orals, externals, Bulk concentrates.


Session 24

Procurement of stores and testing of raw materials.


Session 25

Nomenclature and uses of surgical instruments .


Session 26

Hospital Equipments and health accessories.


Session 27

P.T.C.(pharmacy Therapeutic Committee) .

pharmacy and therapeutics committee(PTC)

Session 28

Hospital Formulary system and their organization, functioning, composition.

Hospital Formulary

Session 29

Drug Information service and Drug Information Bulletin.


Session 30

Surgical dressing like cotton, gauze, bandages .

surgical dressing-converted

Session 31

Adhesive tapes including their pharmacopoeial tests for quality.

surgical dressing-converted

Session 32

Other hospital supply eg. I.V.sets, B.G. sets .


Session 34

Catheters .


Session 35

Syringes .


Session 36

Application of computers in maintenance of records, inventory control.

Application of Computers

Session 37

Medication monitoring .


Session 39

Data storage and retrieval in hospital retail pharmacy establishment.


Session 40

Introduction to Clinical pharmacy practice- Definition, scope.

Chapter 1 - Definitions, development and scope of clinical pharmacy 16.08.2010

Session 41

Modern dispensing aspects- Pharmacists and patient counseling .

Patient counselling-converted

Session 42

Modern dispensing aspects- Pharmacists and patient counseling .

Patient counselling-converted

Session 43

Session 44

Common daily terminology used in the practice of Medicine.

daily terminology-converted

Session 45

Disease, manifestation and patho-physiology including salient symptoms to understand the disease like :

Tuberculosis .


Session 47

Rheumatoid Arthritis .


Session 48

Cardio-vascular diseases .


Session 49


Epilepsy I (2)

Session 50

Session 51

Peptic Ulcer .


Session 52



Session 53

Physiological parameters with their significance.


Session 54

Drug Interactions: Definition and introduction.


Session 55

Mechanism of Drug Interaction.


Session 56

Drug-drug interaction with reference to analgesics .


Session 57

Session 58

Session 59

Gastro-intestinal agents.


Session 60

Session 61

Hypoglycemic agents.


Session 62

Session 63

Adverse Drug Reaction: Definition and significance.


Session 64

Module: 64
Drug-Induced diseases and Teratogenicity.


Session 65

Drugs in Clinical Toxicity- Introduction, general treatment of poisoning, systemic antidotes .

Toxicology Principles of Management of Acute Poisoning

Session 66

Treatment of insecticide poisoning, heavy metal poison .

Heavy metal poisoning

Session 67

Narcotic drugs.

Dispensing of narcotics

Session 68

Barbiturate, Organo-phosphorus poisons .

Barbiturates and benzodiazepines - Copy

Session 69

Drug dependences, Drug abuse.

Dispensing of narcotics

Session 70

Addictive drugs and their treatment, complications.

Dispensing of narcotics

Session 71

Bio-availability of drugs, including factors affecting it.

Assessing Bioavailablility of Drug Delivery Systems

Experiment no: 01

To study about the moist heat sterilization by using Autoclave .


Experiment no: 02

To sterilize the given material by using Autoclave


Experiment no: 03

To study about the dry heat sterilization by using Hot Air Oven .


Experiment no: 04

To sterilize the glassware by using Hot Air Oven .


Experiment no: 05

To prepare 500 ml of sterile Sodium chloride injection I.P.

500ml sodium chloride

Experiment no: 06

 To prepare 50 ml of 5% Dextrose solution & sterile it by filtration method .

dextrose solution

Experiment no: 07

To study various equipment, materials & clothing used in a aseptic of 5% Dextrose solution & sterile it by filtration method

Experiment no: 08

 To study various components of computers


Experiment no: 09

To perform test for cotton (absorbent cotton)


Experiment no: 10

 To prepare 100 ml of sodium lactate injection I.P.

sodium lactate inj.-converted

Experiment: 11

 To Study about the Nomenclature and uses of Surgical Instruments


Experiment no: 12

To study about different types of Syringes


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