PATHOPHYSIOLOGY By Rupali Rupasmita Rout
per person /
Free
Pathophysiology Theory(2nd Sem)
Teacher
Rupali Rupasmita Rout
Category
Core Courses
Course Attendees
Still no participant
Course Reviews
Still no reviews
Course Objective:
Pathophysiology is the study of causes of diseases and reactions of the body to such disease producing causes.This course is designed to impart a thorough knowledge of the relevant aspects of pathology of various conditions with reference to its pharmacological applications, and understanding of basic pathophysiological mechanisms. Hence it will not only help to study the syllabus of pathology, but also toget baseline knowledge required to practice medicine safely, confidently, rationally and effectively.
COURSE OUTCOMES:
| COs | Statements |
| CO-1 | Describe the etiology and pathogenesis of the selected disease states. |
| CO-2 | Name the signs and symptoms of the diseases. |
| CO-3 | Able to apply basic principles of cell injury and inflammation in understanding various diseases. |
| CO-4 | To get skill in analysing various pathophysiological changes in major systems of human body and correlate with diseases. |
| CO-5 | Able to correlate relation between pathophysiology and clinical skills. |
COs & POs MAPPING:
| SNO | COs | COs & POs
MAPPING |
| 1 | Describe the aetiology and pathogenesis of the selected disease states. | PO1,PO2,PO6,PO7,PO11 |
| 2 | Name the signs and symptoms of the diseases. | PO1, PO6,PO7 |
| 3 | Able to apply basic principles of cell injury and inflammation in understanding various diseases. | PO1,PO2,PO6,PO7 |
| 4 | To get skill in analysing various pathophysiological changes in major systems of human body and correlate with diseases. | PO1,PO2, PO3 |
| 5 | Able to correlate relation between pathophysiology and clinical skills. | PO1,PO2,PO3,PO11 |
Course content:
Unit I
Basic principles of Cell injury and Adaptation:
Introduction, definitions, Homeostasis, Components and Types of Feedback systems,Causes of cellular injury,Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage),Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis & Alkalosis,Electrolyte imbalance
Basic mechanism involved in the process of inflammation and repair:
Introduction, Clinical signs of inflammation, Different types of
Inflammation,Mechanism of Inflammation – Alteration in vascular permeability and blood flow, migration of WBC’s,Mediators of inflammation,Basic principles of wound healing in the skin,Pathophysiology of Atherosclerosis
Unit II
Cardiovascular System:
Hypertension, congestive heart failure, ischemic heart disease (angina,myocardial infarction, atherosclerosis and arteriosclerosis)
Respiratory system: Asthma, Chronic obstructive airways diseases.
Renal system: Acute and chronic renal failure.
Unit III
Haematological Diseases:
Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, hemophilia
Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones
Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders:
depression, schizophrenia and Alzheimer’s disease.
Gastrointestinal system: Peptic Ulcer
Unit IV
Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver
disease. Disease of bones and joints: Rheumatoid arthritis, osteoporosis and gout Principles of cancer: classification, etiology and pathogenesis of cancer
Diseases of bones and joints: Rheumatoid Arthritis, Osteoporosis,Gout
Principles of Cancer: Classification, etiology and pathogenesis of Cancer
Unit V
Infectious diseases: Meningitis, Typhoid, Leprosy, Tuberculosis, Urinary tract
infections. Sexually transmitted diseases: AIDS, Syphilis, Gonorrhea
SESSION:1
Introduction, definitions, Homeostasis, Components and Types of Feedback systems
Session 2:
Causes of cellular injury,Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage)
Session 3:
Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia)
Session 4:
Cell swelling, Intra cellular accumulation, Calcification, Acidosis &Alkalosis, Electrolyte imbalance
Session 6:
Introduction, Clinical signs of inflammation, Different types of Inflammation
Session 7:
Mechanism of Inflammation – Alteration in vascular permeability and blood flow, migration of WBC’s, Mediators of inflammation
Session 8:
Basic principles of wound healing in the skin
Session 37:
Disease of bones and joints: Rheumatoid arthritis, Osteoporosis and Gout
Session 39:
Infectious diseases: Meningitis, Typhoid, Leprosy, Tuberculosis
Our Main Teachers