Pharmaceutical Analysis Practical- I
Teacher
Dr. BIKASH RANJAN JENA, M.Pharm., Ph.D
Category
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Course Objectives
After completion of course student is able to know,
Chemicals and Excipients
The analysis of various drugs in single and combination dosage forms
Theoretical and practical skills of the instrument
Scope
This subject deals with various advanced analytical instrumental techniques for
identification, characterization and quantification of drugs. Instruments dealt are
NMR, Mass spectrometer, IR, HPLC, GC etc.
Course Outcome:
| CO | Statement | Mapping with POs |
| CO-1 | Understand the interaction of matter with electromagnetic radiations and its applications in drug analysis | PO1, PO2, PO8 |
| CO-2 | Understand the chromatographic separation and analysis of drugs. | PO1, PO6, PO9 |
| CO-3 | Perform quantitative & qualitative analysis of drugs using various analytical instruments. | PO1, PO2, PO8 |
| CO-4 | Able to separate and analyses drugs by chromatography Radioimmunoassay and Electrophoresis | PO1, PO3, PO6, PO8 |
| CO-5 | student interpretation skills will be improve by the course content in terms of choice of analytical techniques to perform the estimation of different category drugs. | PO1, PO2, PO6 |
SYLLABUS
- Analysis of Pharmacopoeial compounds and their formulations by UV Vis spectrophotometer
- Simultaneous estimation of multi component containing formulations by UV spectrophotometry.
- Experiments based on HPLC
- Experiments based on Gas Chromatography
- Estimation of riboflavin/quinine sulphate by fluorimetry
- Estimation of sodium/potassium by flame photometry
- Assay of official compounds by different titrations
- Assay of official compounds by instrumental techniques.
- Quantitative determination of hydroxyl group.
- Quantitative determination of amino group
- Colorimetric determination of drugs by using different reagents
- Imupurity profiling of drugs
- Calibration of glasswares
- Calibration of pH meter
- Calibration of UV-Visible spectrophotometer
- Calibration of FTIR spectrophotometer
- Calibration of GC instrument
- Calibration of HPLC instrument
- Cleaning validation of any one equipment
- Determination of total reducing sugar
- Determination of proteins
- Determination of saponification value, Iodine value, Peroxide value, Acid value in food products
- Determination of fat content and rancidity in food products
- Analysis of natural and synthetic colors in food
- Determination of preservatives in food
- Determination of pesticide residue in food products
- Analysis of vitamin content in food products
- Determination of density and specific gravity of foods
- Determination of food additives
Session 1
Simultaneous Estimation of Multicomponent Containing Formulations Using UV Spectrophotometry
Session 2
Estimation of Salicylic Acid by Colorimetric Methods
Session 3
Determination of Maximum Wavelength Of KMNO4
Session 4
Determination Effect of Concentration Of Absorbance Maximum Of Potasium Permanganate
Session 5
Estimation of riboflavin/quinine sulphate by fluorimetry
Session 6
Estimation of Dextrose In Sample By Colorimetry
Session 7
Separation and Identification of Aminoacids By Paper Chromatography
Session 8
Determination of Pka Value Of Acetic Acid Using Potentiometry
Session 9
Determination of Sulphate limit in Calcium gluconate using Nephlo-Turbidimetry.
Session 10
Determination of saponification value, Iodine value, Acid value in food products
Our Main Teachers
About Me My self Dr.Bikash Ranjan Jena currently working in Pharmaceutical Analysis & Research Division, School of Pharmacy and Life Sciences (SoPLS), Centurion University, Bhubaneswar since Jan 2021. I have successfully awarded my Ph.D degree at KLEF Deemed to be University, Vaddeswaram, Guntur, A.P on 22nd June 2023. Expertised in Analytical Quality by Design (AQbD), […]