Course Objectives

This subject deals with identification, characterization of simple organic compounds based upon their solunility, melting point, boiling point determination, Elemental analysis, and by characteristic chemical test and also to synthesize some simple organic compounds and derivatives.

Learning Outcomes

• Students will be able to Identify and characterize of simple organic compounds
• Students will be able to synthesize simple organic compounds and their derivatives.

Course Syllabus

1. Systematic qualitative analysis of unknown organic compounds like
1. Preliminary test: Color, odour, aliphatic/aromatic compounds, saturation and unsaturation, etc.
2. Detection of elements like Nitrogen, Sulphur and Halogen by Lassaigne’s test
3. Solubility test
4. Functional group test like Phenols, Amides/ Urea, Carbohydrates, Amines, Carboxylic acids, Aldehydes and Ketones, Alcohols, Esters, Aromatic and Halogenated Hydrocarbons, Nitro compounds and Anilides.
5. Melting point/Boiling point of organic compounds
6. Identification of the unknown compound from the literature using melting point/ boiling point.
7. Preparation of the derivatives and confirmation of the unknown compound by melting point/ boiling point.
8. Minimum 5 unknown organic compounds to be analysed systematically.
9. Preparation of suitable solid derivatives from organic compounds
10. Construction of molecular models.

Session Plan

Session 8

To perform the Functional group test of Carboxylic acids, Aldehydes and Ketones.

Text Material: Experiment 8 of Laboratory manual-Pharmaceutical Organic Chemistry-I (Practical Manual-Pharmaceutical Organic Chemistry - I ) Video Link Functional group test of Carboxylic acids: https://youtu.be/E2xNpSj_A4U. Video Link Functional group test of Aldehydes: https://youtu.be/X7ZJqLEhX9k.  Video Link Functional group test of Ketones: https://youtu.be/JAQ060bSZG8

Session 10

To Perform the functional group test for Nitro compounds and Anilides.

Text Material: Experiment 10 of Laboratory manual-Pharmaceutical Organic Chemistry-I (Practical Manual-Pharmaceutical Organic Chemistry - I ). Video Link For functional group test for Nitro compounds: https://youtu.be/K6kh7p1TPBs. Video link For functional group test for Anilides:  https://youtu.be/yFFeI8yraRM

Session 11

To Perform the Melting point determination of the supplied organic compound.

Text Material: Experiment 11 of Laboratory manual-Pharmaceutical Organic Chemistry-I (Practical Manual-Pharmaceutical Organic Chemistry - I ). Video Link: https://youtu.be/nQNaTfqXECk

Session 12

To perform the determination of Boiling point of the supplied organic compound.

Text Material: Experiment 12 of Laboratory manual-Pharmaceutical Organic Chemistry-I (Practical Manual-Pharmaceutical Organic Chemistry - I ). Video Link: https://youtu.be/8b5Ha-8QGhY

Session 13

To synthesize and characterize Iodoform from ethyl alcohol (Haloform Test).

Text Material: Experiment 13 of Laboratory manual-Pharmaceutical Organic Chemistry-I (Practical Manual-Pharmaceutical Organic Chemistry - I ). Video Link: https://youtu.be/PPL-7M8rrNU

Session 14

To synthesize and characterize Thiourea

Text Material: Experiment 14 of Laboratory manual-Pharmaceutical Organic Chemistry-I (Practical Manual-Pharmaceutical Organic Chemistry - I )