Pharmaceutical Organic Chemistry -I (Practical)
Teacher
Biswajit Samantaray
Category
Core Courses
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Course Name : Pharmaceutical Organic Chemistry -I (Practical)
Code(Credit) : BPHL1202(0-2-0)
Course Objectives
- This subject deals with classification and nomenclature of simple organic
compounds, structural isomerism, intermediates forming in reactions, important physical
properties, reactions and methods of preparation of these compounds. The syllabus also
emphasizes on mechanisms and orientation of reactions.
Course Outcomes
| CO | Statements | PO MAPPING |
| CO-1 | Able to acquire knowledge about pharmaceutical organic compounds, with emphasis on their synthetic process, physical and chemical properties and compare them with each other | PO1, PO2, PO11 |
| CO-2 | Able to write mechanisms involved in various reactions that could help the students to understand the synthesis of higher organic compounds. | PO1, PO2, PO5, PO11 |
| CO-3 | Account for reactivity/stability of compounds, | PO1, PO2, PO11 |
| CO-4 | Identify/confirm the identification of organic compound | PO1, PO2, PO11 |
| CO-5 | Able to analyze various reactions for the synthesis of higher organic compounds. | PO1, PO2, PO5, PO11 |
Course Syllabus
Systematic qualitative analysis of unknown organic compounds like
1. Preliminary test: Color, odour, aliphatic/aromatic compounds, saturation
and unsaturation, etc.
2. Detection of elements like Nitrogen, Sulphur and Halogen by
Lassaigne’s test
3. Solubility test
4. Functional group test like Phenols, Amides/ Urea, Carbohydrates,
Amines, Carboxylic acids, Aldehydes and Ketones, Alcohols, Esters,
Aromatic and Halogenated Hydrocarbons, Nitro compounds and
Anilides.
5. Melting point/Boiling point of organic compounds
6. Identification of the unknown compound from the literature using
melting point/ boiling point.
7. Preparation of the derivatives and confirmation of the unknown
compound by melting point/ boiling point.
8. Minimum 5 unknown organic compounds to be analyzed systematically. 2. Preparation of suitable solid derivatives from organic compounds
Session Plan
Session 1
Preliminary test: Color, odour, aliphatic/aromatic compounds, saturation
and unsaturation
Session 2
Detection of elements like Nitrogen, Sulphur and Halogen by
Lassaigne’s test
https://www.youtube.com/watch?v=7vKQuWWgULw
Session 4
Functional group test like Phenols, Amides/ Urea, Carbohydrates,
Amines, Carboxylic acids, Aldehydes and Ketones, Alcohols, Esters,
Aromatic and Halogenated Hydrocarbons, Nitro compounds and
Anilides
Session 5
Melting point/Boiling point of organic compounds
Session 6
Identification of the unknown compound from the literature using
melting point/ boiling point.
Session 7
Preparation of the derivatives and confirmation of the unknown
compound by melting point/ boiling point.
Session 8
Minimum 5 unknown organic compounds to be analysed systematically.
Session 9
Preparation of suitable solid derivatives from organic compounds
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Case Studies
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