Pharmaceutical Organic Chemistry -I (Practical)

Teacher

Biswajit Samantaray

Category

Core Courses

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Course Name : Pharmaceutical Organic Chemistry -I (Practical)

Code(Credit) : BPHL1202(0-2-0)

Course Objectives

  • This subject deals with classification and nomenclature of simple organic
    compounds, structural isomerism, intermediates forming in reactions, important physical
    properties, reactions and methods of preparation of these compounds. The syllabus also
    emphasizes on mechanisms and orientation of reactions.

Course Outcomes

CO Statements PO MAPPING
CO-1 Able to acquire knowledge about pharmaceutical organic compounds, with emphasis on their synthetic process, physical and chemical properties and compare them with each other PO1, PO2, PO11
CO-2 Able to write mechanisms involved in various reactions that could help the students to understand the synthesis of higher organic compounds. PO1, PO2, PO5, PO11
CO-3 Account for reactivity/stability of compounds, PO1, PO2, PO11
CO-4 Identify/confirm the identification of organic compound PO1, PO2, PO11
CO-5 Able to analyze various reactions for the synthesis of higher organic compounds. PO1, PO2, PO5, PO11

Course Syllabus

Systematic qualitative analysis of unknown organic compounds like
1. Preliminary test: Color, odour, aliphatic/aromatic compounds, saturation
and unsaturation, etc.
2. Detection of elements like Nitrogen, Sulphur and Halogen by
Lassaigne’s test
3. Solubility test
4. Functional group test like Phenols, Amides/ Urea, Carbohydrates,
Amines, Carboxylic acids, Aldehydes and Ketones, Alcohols, Esters,
Aromatic and Halogenated Hydrocarbons, Nitro compounds and
Anilides.
5. Melting point/Boiling point of organic compounds
6. Identification of the unknown compound from the literature using
melting point/ boiling point.
7. Preparation of the derivatives and confirmation of the unknown
compound by melting point/ boiling point.
8. Minimum 5 unknown organic compounds to be analyzed systematically. 2. Preparation of suitable solid derivatives from organic compounds

Session Plan

Session 1

Preliminary test: Color, odour, aliphatic/aromatic compounds, saturation
and unsaturation

https://www.youtube.com/watch?v=E2xNpSj_A4U

Session 2

Detection of elements like Nitrogen, Sulphur and Halogen by
Lassaigne’s test

 

https://www.youtube.com/watch?v=7vKQuWWgULw

https://www.youtube.com/watch?v=F8m3ti2FoAc

https://www.youtube.com/watch?v=FUo428guKt0

Session 4

Functional group test like Phenols, Amides/ Urea, Carbohydrates,
Amines, Carboxylic acids, Aldehydes and Ketones, Alcohols, Esters,
Aromatic and Halogenated Hydrocarbons, Nitro compounds and
Anilides

https://edu.rsc.org/resources/qualitative-tests-for-organic-functional-groups-practical-videos-16-18-students/4012307.article

https://www.youtube.com/watch?v=n4esSHxz_J8

http://amrita.olabs.edu.in/?sub=73&brch=8&sim=141&cnt=715

Session 5

Session 8

Minimum 5 unknown organic compounds to be analysed systematically.

https://www.youtube.com/watch?v=zMuPxeIiiNA

Session 10

Construction of molecular models

https://www.youtube.com/watch?v=DTk3BlXG3hA

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