Course Objectives

• This course is designed to impart knowledge and skills necessary to train the students to be on par with the routine of Industrial activities in Production

Learning Outcomes

• On completion of this course it is expected that students will be able to
  understand,
   Handle the scheduled activities in a Pharmaceutical firm.
   Manage the production of large batches of pharmaceutical
  formulations.

Course Syllabus

Module I

Improved Tablet Production: Tablet production process, unit operation improvements, granulation and pelletization equipments, continuous and batch mixing, rapid mixing granulators, rota granulators, spheronizers and marumerisers, and other specialized granulation and drying equipments.
Problems encountered.
Coating Technology: Process, equipments, particle coating,
fluidized bed coating, application techniques. Problems
encountered.

Module II

Parenteral Production: Area planning & environmental control,
wall and floor treatment, fixtures and machineries, change rooms,
personnel flow, utilities & utilities equipment location, engineering
and maintenance.

Module III

Lyophilization & Spray drying Technology: Principles, process, freeze-drying and spray drying equipments.

Module IV

Capsule Production: Production process, improved capsule
manufacturing and filling machines for hard and soft gelatin
capsules. Layout and problems encountered.

Disperse Systems Production: Production processes,
applications of mixers, mills, disperse equipments including fine
solids dispersion, problems encountered.

Packaging Technology: Types of packaging materials,
machinery, labeling, package printing for different dosage forms.

Module V

Air Handling Systems: Study of AHUs, humidity & temperature
control, air filtration systems, dust collectors.

Water Treatment Process: Techniques and maintenance – RO, DM, ultrafiltration, WFI.

Session Plan

Session 1

Tablet production process

Session 2

Unit operation improvements

Session 3

Granulation and palletization equipments

Session 4

Continuous and batch mixing

Session 5

Rapid mixing granulators

Session 6

Rota granulators

Session 7

Spheronizers and marumerisers

Session 8

Other specialized granulation

Session 9

Drying equipment's

Session 10

Problems encountered

Session 11

Coating technology process

Session 12

Coating technology equipment

Session 13

Particle coating

Session 14

Fluidized bed coating

Session 15

Application techniques

Session 16

Problems encountered

Session 17

Parenteral Production area planning

Session 18

Parenteral Production environmental control

Session 19

wall and floor treatment

Session 20

Fixtures and machineries

Session 21

change rooms, personnel flow

Session 22

Utilities & utilities equipment location

Session 23

Engineering and maintenance

Session 24

Lyophilization & Spray drying Technology

Session 25

freeze-drying and spray drying equipment's

Session 26

Spray drying Technology

Session 27

Production process

Session 28

Improved capsule production

Session 29

Filling machines for hard and soft gelatin capsule

Session 30

Layout and problems encountered

Session 31

Applications of mixers

Session 32

Mills

Session 33

Disperse equipments including fine

Session 34

Problems encountered

Session 35

Types of packaging materials

Session 36

Machinery

Session 37

Labeling, package printing for different dosage forms

Session 38

Air Handling Systems

Session 39

Humidity & temperature control

Session 40

Air filtration systems

Case Studies

Case Studies