Theory
Introduction to Pharmacology: History, Importance, Terms and Definitions, Drug development, Screening and Nomenclature, Scope of pharmacology in fishes. Route of Administration and Method of application to fish. Source of Drugs.Pharmacolotherapeutic classification of drugs. Pharmacokinetics: Biological membrane, absorption, distribution, biotransformation and Excretion of drugs. Factors influencing drug metabolism. Pharmacodynamics: Principles of drug action, concept of drug receptor, nature, chemistry, classification. Functions of receptor. Transducer mechanism, second messenger, non receptor mediated action. Dose Response Relationship, half life withdrawal period, potency, efficacy, threshold dose, therapeutic dose, maximal dose, toxic dose, lethal dose. Factors modifying drug action, Adverse drug effects, drug interaction and Bioassay of drugs. Salient features in drug acting on digestive system, and reproductive system. Drugs used in fish transporation. Drug resistance. Recent advances in Pharmacology, biostatistics in experimental Pharmacology, Pharmaceutical industry for aqua-medicines.
Practicals
Introduction to Pharmacy, Metrology, Prescription Writing, Preparation of drug solution for fish/shellfishes, Source and chemical nature of drugs, Incompatability, Pharmacutical technology, Bioassay of drugs, Animal models in Pharmacological experiments, Methods of application of drugs in fish/ Aquaculture.
Suggested Readings-
Fish Pharmacology and Toxicology –Govind Pandey
Applied Fish Pharmacology - K.M.T.Brown
Fish Pathology -Ronald J. Roberts