Pharmacology II

Teacher

Mrs. Prachi Rani Sahu

Category

Core Courses

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Course Name : Pharmacology II

Code(Credit) : BPHT3103(4-0-0)

Course Objectives

  • This subject is intended to impart the fundamental knowledge on various aspects (classification, mechanism of action, therapeutic effects, clinical uses, side effects and contraindications) of drugs acting on different systems of body and in addition,emphasis on the basic concepts of bioassay.

Learning Outcomes

  • Upon completion of this course the student should be able to
    1. Understand the mechanism of drug action and its relevance in the treatment of
    different diseases
    2. Demonstrate isolation of different organs/tissues from the laboratory animals by
    simulated experiments
    3. Demonstrate the various receptor actions using isolated tissue preparation
    4. Appreciate correlation of pharmacology with related medical sciences.

Course Syllabus

MODULE-I
1. Pharmacology of drugs acting on cardio vascular system
a. Introduction to hemodynamic and electrophysiology of heart.
b. Drugs used in congestive heart failure
c. Anti-hypertensive drugs.
d. Anti-anginal drugs.
e. Anti-arrhythmic drugs.
f. Anti-hyperlipidemic drugs. 10hours
MODULE-II
1. Pharmacology of drugs acting on cardio vascular system
a. Drug used in the therapy of shock.
b. Hematinics, coagulants and anticoagulants.
c. Fibrinolytics and anti-platelet drugs
d. Plasma volume expanders
2. Pharmacology of drugs acting on urinary system
a. Diuretics
b. Anti-diuretics. 10hours
MODULE-III
3. Autocoids and related drugs
a. Introduction to autacoids and classification
b. Histamine, 5-HT and their antagonists.
c. Prostaglandins, Thromboxanes and Leukotrienes.
d. Angiotensin, Bradykinin and Substance P.
e. Non-steroidal anti-inflammatory agents
f. Anti-gout drugs

MODULE-IV
5. Pharmacology of drugs acting on endocrine system
a. Basic concepts in endocrine pharmacology.
b. Anterior Pituitary hormones- analogues and their inhibitors.
c. Thyroid hormones- analogues and their inhibitors.
d. Hormones regulating plasma calcium level- Parathormone, Calcitonin and
Vitamin-D.
d. Insulin, Oral Hypoglycemic agents and glucagon.
e. ACTH and corticosteroids.
MODULE-V
5. Pharmacology of drugs acting on endocrine system
a. Androgens and Anabolic steroids.
b. Estrogens, progesterone and oral contraceptives.
c. Drugs acting on the uterus.
6. Bioassay
a. Principles and applications of bioassay.
b.Types of bioassay
c. Bioassay of insulin, oxytocin, vasopressin, ACTH,d-tubocurarine,digitalis,      histamine and 5-HT

Recommended Books (Latest Editions)
1. Rang H. P., Dale M. M., Ritter J. M., Flower R. J., Rang and Dale’s
Pharmacology,.Churchil Livingstone Elsevier
2. Katzung B. G., Masters S. B., Trevor A. J., Basic and clinical pharmacology, Tata Mc
Graw-Hill
3.Goodman and Gilman’s, The Pharmacological Basis of Therapeutics
4. Marry Anne K. K., Lloyd Yee Y., Brian K. A., Robbin L.C., Joseph G. B., Wayne A.
K., Bradley R.W., Applied Therapeutics, The Clinical use of Drugs, The Point LippincottWilliams & Wilkins
5. Mycek M.J, Gelnet S.B and Perper M.M. Lippincott’s Illustrated Reviews-
Pharmacology

6.K.D.Tripathi. Essentials of Medical Pharmacology, JAYPEE Brothers Medical
Publishers (P) Ltd, New Delhi.
7. Sharma H. L., Sharma K. K., Principles of Pharmacology, Paras medical publisher
8. Modern Pharmacology with clinical Applications, by Charles R.Craig& Robert,
9.Kulkarni SK. Handbook of experimental pharmacology. VallabhPrakashan,
10.Ghosh MN. Fundamentals of Experimental Pharmacology. Hilton & Company,
Kolkata.

Session Plan

Session 1

Introduction to hemodynamic and electrophysiology of heart.

PDF- electrophysiology of heart-converted

haemodyanamic and electrophysiology of heart

Session 2

Drugs used in congestive heart failure

pharmacologicalmanagementofheartfailure-171027075756

Session 3

Anti-hypertensive drugs.

Anti-hypertensive drugs

Session 4

Anti-anginal drugs.

anti anginal drugs-converted

Session 5

Anti-arrhythmic drugs.

e020434.full(1)Anti-arrhythmic drugs

Session 6

Anti-hyperlipidemic drugs.

hyperlipidemiamoa-180513091325

Session 7

Drug used in the therapy of shock.

pharmacotherapyofshock-150914063608-lva1-app6892

Session 8

Hematinics, coagulants and anticoagulants

coagulantandanticoagulant-170905090544

Session 9

Fibrinolytics and anti-platelet drugs

fibrinolyticsantiplateletsnaser-121122033439-phpapp01

Session 10

Plasma volume expanders

plasma volume expanders

Session 11

Session 12

Session 13

autocoids and its classification

autacoids-180506141516

Session 14

Histamine, 5-HT and their antagonists.

autacoids-180506141516

Session 15

Prostaglandins, Thromboxanes and Leukotrienes.

autacoids-180506141516

Session 16

Angiotensin, Bradykinin and Substance P.

autacoids-180506141516

Session 17

Session 18

Anti-gout drugs

antigout-190912172530

Session 19

Antirheumatic drugs

antirheumatoiddrugs-161125184115

Session 20

Basic concepts in endocrine pharmacology

endocrinepharma-171226191027

Session 21

Anterior Pituitary hormones- analogues and their inhibitors

endocrinepharma-171226191027

Session 22

Thyroid hormones- analogues and their inhibitors

endocrinepharma-171226191027

Session 23

Hormones regulating plasma calcium level- Parathormone, Calcitonin and
Vitamin-D

endocrinepharma-171226191027

Session 24

Insulin, Oral Hypoglycemic agents and glucagon.

endocrinepharma-171226191027

Session 25

ACTH and corticosteroids

endocrinepharma-171226191027

Session 26

Androgens and Anabolic steroids

endocrinepharma-171226191027

Session 27

Estrogens, progesterone and oral contraceptives.

endocrinepharma-171226191027

Session 29

Principles and applications of bioassay.

principlestypesofbioassay-180309134847

Session 28

Drugs acting on the uterus.

endocrinepharma-171226191027

Session 29

Principles and applications of bioassay.

principlestypesofbioassay-180309134847

Session 30

Session 31

Session 32

oxytocin, vasopressin, ACTH,d-tubocurarine

principlestypesofbioassay-180309134847

Session 33

digitalis, histamine and 5-HT

principlestypesofbioassay-180309134847

Session 32

oxytocin, vasopressin, ACTH,d-tubocurarine

principlestypesofbioassay-180309134847

Case Studies

Case Studies

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