Pharmacology-III

Teacher

SUCHARITA BABU

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Course Name : Pharmacology-III

Course code: BPHT3202 (4-0-0)

Course Objective: This subject is intended to impart the fundamental knowledge on various aspects (classification, mechanism of action, therapeutic effects, clinical uses, side effects and contraindications) of drugs acting on respiratory and gastrointestinal system, infectious diseases, immune-pharmacology and in addition, emphasis on the principles of toxicology and chrono-pharmacology

Course Outcomes: On completion of this course, the successful students should be able to:

CO	Statement	Mapping with PO
CO-1	Understand the mechanism of drug action and its relevance in the treatment of different infectious diseases	PO1
CO-2	Comprehend the principles of toxicology and treatment of various poisonings	PO1,PO2
CO-3	Appreciate correlation of pharmacology with related medical sciences.	PO1,PO3
CO-4	Able to appraise the principles of pharmacology aspects of various Drugs	PO1,PO2,
CO-5	To get knowledge for the practical skills required to conduct the preclinical toxicity studies.	PO1,PO2,PO10,

Course Syllabus

UNIT-I 10hours
1. Pharmacology of drugs acting on Respiratory system
a. Anti -asthmatic drugs
b. Drugs used in the management of COPD
c. Expectorants and antitussives
d. Nasal decongestants
e. Respiratory stimulants
2. Pharmacology of drugs acting on the Gastrointestinal Tract
a. Antiulcer agents.
b. Drugs for constipation and diarrhoea.
c. Appetite stimulants and suppressants.
d. Digestants and carminatives.
e. Emetics and anti-emetics.
UNIT-II 10hours
3. Chemotherapy
a. General principles of chemotherapy.
b. Sulfonamides and cotrimoxazole.
c. Antibiotics- Penicillins, cephalosporins, chloramphenicol, macrolides, quinolones
and fluoroquinolins, tetracycline and aminoglycosides
UNIT-III 10hours
3. Chemotherapy
a. Antitubercular agents
b. Antileprotic agents
c. Antifungal agents
d. Antiviral drugs
e.Anthelmintics
f. Antimalarial drugs
g. Antiamoebic agents
UNIT-IV 08hours
3. Chemotherapy
l. Urinary tract infections and sexually transmitted diseases.
m. Chemotherapy of malignancy.
4. Immunopharmacology
a. Immunostimulants
b. Immunosuppressant
Protein drugs, monoclonal antibodies, target drugs to antigen, biosimilars
UNIT-V 7hours
5. Principles of toxicology
a. Definition and basic knowledge of acute, subacute and chronic toxicity.
b. Definition and basic knowledge of genotoxicity, carcinogenicity, teratogenicity and
mutagenicity
c. General principles of treatment of poisoning
d. Clinical symptoms and management of barbiturates, morphine,
organophosphosphorus compound and lead, mercury and arsenic poisoning.
6. Chronopharmacology
a. Definition of rhythm and cycles.
b. Biological clock and their significance leading to chronotherapy.