Pharmacology III Practical
Teacher
Ashirbad Nanda
Category
Core Courses
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Course Name: Pharmacology III (Practical)
Code(Credit) : BPHL3202 (0-2-0)
Course Objectives
This subject is intended to impart fundamental knowledge on various aspects (classification, mechanism of action, therapeutic effects, clinical uses, side effects, and contraindications) of drugs acting on the respiratory and gastrointestinal system, infectious diseases, immune-pharmacology and in addition, emphasis on the principles of toxicology and chrono-pharmacology.
Course outcome
| CO | Statement | Mapping with POs |
| CO-1 | Understand the mechanism of drug action and its relevance in the treatment of different infectious diseases
|
PO1, PO2, PO3, PO10 |
| CO-2 | Comprehend the principles of toxicology and treatment of various poisonings
|
PO1, PO2, PO5, PO6 |
| CO-3 | Appreciate the correlation of pharmacology with related medical sciences.
|
PO1, PO2, PO5, PO6 |
| CO-4 | Able to appraise the principles of pharmacology aspects of various rugs
|
PO1, PO2, PO3, PO6 |
| CO-5 | To get knowledge for the practical skills required to conduct preclinical toxicity studies.
|
PO1, PO5, PO6 |
Course Syllabus
1. Dose calculation in pharmacological experiments
2. Antiallergic activity by mast cell stabilization assay
3. Study of anti-ulcer activity of a drug using pylorus ligand (SHAY) rat model and
NSAIDS induced ulcer model.
4. Study of effect of drugs on gastrointestinal motility
5. Effect of agonist and antagonists on guinea pig ileum
6. Estimation of serum biochemical parameters by using semi- autoanalyser
7. Effect of saline purgative on frog intestine
8. Insulin hypoglycemic effect in rabbit
9. Test for pyrogens ( rabbit method)
10. Determination of acute oral toxicity (LD50) of a drug from a given data
11. Determination of acute skin irritation / corrosion of a test substance
12. Determination of acute eye irritation / corrosion of a test substance
13. Calculation of pharmacokinetic parameters from a given data
14. Biostatistics methods in experimental pharmacology( student’s t test, ANOVA)
15. Biostatistics methods in experimental pharmacology (Chi square test, Wilcoxon
Signed Rank test)
Session Plan
Session 1
1. Dose calculation in pharmacological experiments
Session 2
2. Antiallergic activity by mast cell stabilization assay
Session 3
3. Study of anti-ulcer activity of a drug using pylorus ligand (SHAY) rat model and NSAIDS induced ulcer model.
Session 6
6. Estimation of serum biochemical parameters by using semi- autoanalyser
Session 10
10. Determination of acute oral toxicity (LD50) of a drug from a given data
Session 11
11. Determination of acute skin irritation / corrosion of a test substance
Session 12
12. Determination of acute eye irritation / corrosion of a test substance
https://www.slideshare.net/ajaymandal/acute-eye-irritationcorrosion-405
Session 13
13. Calculation of pharmacokinetic parameters from a given data
Session 14
14. Biostatistics methods in experimental pharmacology( student’s t test, ANOVA)
https://www.slideshare.net/DrShovanPadhy1/student-t-test
https://www.slideshare.net/snehkhatri/analysis-of-variance-anova
Session 15
15. Biostatistics methods in experimental pharmacology (Chi square test, Wilcoxon Signed Rank test)
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