Course Name: Physical Pharmaceutics-1 (Practical)

Code(Credit):BPHL2102(0-2-0)

Course Objectives

The course deals with the various physical and physicochemical properties, and principles involved in dosage forms/formulations. Practical components of the subject help the student to get a better insight into various areas of formulation research and development, and stability studies of pharmaceutical dosage forms.

Course Outcomes

1. CO	OUTCOMES	PO MAPPING
   CO1	Upon the completion of the course student shall be able to: Solubility of drugs	PO1
   CO2	Understand various physicochemical properties of drug molecules in the designing the dosage form	PO1,PO,PO3
   CO3	Know the principles of chemical kinetics & to use them in assigning expiry date for formulation	PO1,PO11
   CO4	Demonstrate use of physicochemical properties in evaluation of dosage forms.	PO1,PO5
   CO5	Appreciate physicochemical properties of drug molecules in formulation research and development.	PO1,PO2,PO3

Syllabus

1. Determination the solubility of drug at room temperature.

2. Determination of pKa value by Half Neutralization/ Henderson Hasselbalch equation.

3. Determination of Partition co- efficient of benzoic acid in benzene and water.
4. Determination of Partition co- efficient of Iodine in CCl4 and water.
5. Determination of % composition of NaCl in a solution using phenol-water system by CST method.
6. Determination of surface tension of given liquids by drop weight method.
7. Determination of surface tension of given liquids by drop count method.
8. Determination of HLB number of a surfactant by saponification method.
9. Determination of Freundlich and Langmuir constants using activated char coal.
10. Determination of critical micellar concentration of surfactants.

Session Plan

EXPERIMENT-10

Determination of surface tension of given liquids by drop count method.

https://youtu.be/LNm16rbsFQE

EXPERIMENT-9

Determination of critical micellar concentration of surfactants.

https://youtu.be/y3AdOsRAipU

EXPERIMENT-8

Determination of Freundlich and Langmuir constants using activated char coal.

https://youtu.be/vMOa7wrP3w0

EXPERIMENT-7

Determination of HLB number of a surfactant by saponification method.

https://youtu.be/hVjNDeuvjRw

EXPERIMENT-6

Determination of surface tension of given liquids by drop weight method.

https://youtu.be/LNm16rbsFQE

EXPERIMENT-5

Determination of % composition of NaCl in a solution using phenol-water system by CST method.

https://youtu.be/rUX74Uiojyo

EXPERIMENT-4

Determination of Partition co- efficient of Iodine in CCl4 and water.

https://youtu.be/TtqTl1G9gP8

EXPERIMENT-3

Determination of Partition co- efficient of benzoic acid in benzene and water.

https://youtu.be/OExU4B1bMRA

EXPERIMENT-2

Determination of pKa value by Half Neutralization/ Henderson Hasselbalch

equation.

https://youtu.be/lvALYSeDfJo

EXPERIMENT-1

Determination the solubility of drug at room temperature.

https://youtu.be/XwA2m1fsXf4