Course Name: Skill Course - Introduction to Computational Biology
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To foster the students with in silico bioinformatics education for their future career.
• To learn the basic concepts of Bioinformatics and its significance in Biological data analysis.
• To inculcate the advanced tools and databases of genomics and its applications.
• To obtain the hands-on-training in in silico basics related to functional genomics.
Unit 1: History, Scope and Importance, Databases- Tools and their Uses,
Unit 2: Introduction to various tools and databases - DNA Databases - NCBI and its GenBank resources, KEGG and its resources, DNA Data Bank of Japan (DDBJ).
Unit 3: National Centre for Biotechnology Information (NCBI): cDNA libraries and Expressed Sequence Tags (ESTs), EST analysis, Pairwise alignment techniques, Multiple sequence alignment.
Unit 4: Kyoto Encyclopedia of Genes and Genomes (KEGG): Modules, Network, Genomes, Genes and KEGG analysis tools.
Unit 5: DNA Data Bank of Japan (DDBJ): Sequence Alignment Methods, Predictive Methods Using DNA Sequences.
Unit 1: Protein Information Resources (PIR)
Unit 2: SWISS PROT and Protein Data Bank (PDB): Protein features and motifs, annotation and curation, protein structure analysis.
Unit 1: Phylogenetic analysis: Evolution, elements of phylogeny, methods of phylogenetic analysis, Phylogenetic tree of life, comparison of genetic sequence of organisms, phylogenetic analysis tools-Phylip, ClustalW.
Unit 2: BLAST: Basic Local Alignment Search Tool: Nucleotide BLAST, Protein BLAST, Blastn, Blastp, Blastx, tBlastn, tBlastx
Unit 3: Sequence Alignment: MSA using conserved domain and local sequence similarity information, COBALT, Protein sequence alignment, Nucleotide sequence alignment.
Applications of bioinformatics tools in Agriculture, Medicine, Diary, Health Industry, Environment, Biotechnology, Genomics, Transcriptomics and Proteomics; Bioinformatics and Career.
Computational Biology: History, Scope and Importance, Databases - Tools and its applications.
DNA Databases - NCBI and its GenBank resources
DNA Databases - KEGG and its resources
DNA Databases - DNA Data Bank of Japan
cDNA libraries and Expressed Sequence Tags (ESTs)
Expressed Sequence Tags (ESTs)
Multiple sequence alignment
Protein Information Resources (PIR)
Evolution, elements of phylogeny, methods of phylogenetic analysis
Phylogenetic tree of life, comparison of genetic sequence of organisms
Phylogenetic analysis tools-Phylip
BLAST: Basic Local Alignment Search Tool
Sequence Alignment: COBALT
Protein Sequence Alignment
Nucleotide Sequence Alignment
Applications of bioinformatics tools in Agriculture
Applications of bioinformatics tools in Medicine
Applications of bioinformatics tools in Health Industry
Applications of bioinformatics tools in Environment
Applications of bioinformatics tools in Biotechnology
Applications of bioinformatics tools in Genomics
Applications of bioinformatics tools in Transcriptomics
Applications of bioinformatics tools in Proteomics
Bioinformatics and Career
Dr. Pushpalatha Ganesh, Professor & Head in the Department of Plant Biotechnology, M. S. Swaminathan School of Agriculture, Centurion University of Technology and Management, Paralakhemundi, Odisha, India. She possesses more than 11 years of research and teaching experience in Agricultural Biotechnology and Crop Physiology at several national level organizations including DRR, Hyderabad and NRCPB, IARI, […]