NOVEL DRUG DELIVERY SYSTEM

Teacher

Dr. Yashwant Giri

Category

Core Courses

Course Attendees

Still no participant

Course Reviews

Still no reviews

Course Name : NOVEL DRUG DELIVERY SYSTEM

Code(Credit) : BP704T (4-0-0)

Course Objectives

After the completion of the course, students will be able to:

  • Understand the basics of novel drug delivery systems.
  • Understand controlled drug delivery system designs.
  • Explore polymers and targeted drug delivery methods.
  • Apply advanced drug delivery techniques in practice.

Learning Outcomes

On completion of this course, the successful students should be able to:

  • Apprise design principles of controlled drug delivery systems.
  • Assess polymers and microencapsulation in drug formulations.
  • Understand about  transdermal, gastroretentive, and nasopulmonary drug delivery systems.
  • Know about targeted drug delivery methods like liposomes and nanoparticles.
  • Understand the ocular and intrauterine drug delivery systems and their challenges.

Course Syllabus

MODULE-I

Controlled drug delivery systems: Introduction, terminology/definitions and rationale, advantages, disadvantages, selection of drug candidates. Approaches to design controlled release formulations based on diffusion, dissolution and ion exchange principles. Physicochemical and biological properties of drugs relevant to controlled release formulations
Polymers: Introduction, classification, properties, advantages and application of polymers in formulation of controlled release drug delivery systems.

MODULE-II

Microencapsulation: Definition, advantages and disadvantages, microspheres /microcapsules, microparticles, methods of microencapsulation, applications

Mucosal Drug Delivery system: Introduction, Principles of bioadhesion / mucoadhesion, concepts, advantages and disadvantages, transmucosal permeability and formulation considerations of buccal delivery systems

Implantable Drug Delivery Systems: Introduction, advantages and disadvantages, concept of implants and osmotic pump

MODULE-III

Transdermal Drug Delivery Systems: Introduction, Permeation through skin, factors affecting permeation, permeation enhancers, basic components of TDDS, formulation approaches

Gastroretentive drug delivery systems: Introduction, advantages, disadvantages, approaches for GRDDS – Floating, high density systems, inflatable and gastroadhesive systems and their applications

Nasopulmonary drug delivery system: Introduction to Nasal and Pulmonary routes of drug delivery, Formulation of Inhalers (dry powder and metered dose), nasal sprays, nebulizers

MODULE-IV

Targeted drug Delivery: Concepts and approaches advantages and disadvantages, introduction to liposomes, niosomes, nanoparticles, monoclonal antibodies and their applications

MODULE-V

Ocular Drug Delivery Systems: Introduction, intra ocular barriers and methods to overcome –Preliminary study, ocular formulations and ocuserts

 Intrauterine Drug Delivery Systems: Introduction, advantages and disadvantages, development of intra uterine devices (IUDs) and applications

Session Plan

Session 1

Controlled drug delivery systems: Introduction,  terminology/definitions.

PDF- Introduction-1

Session 2

Controlled drug delivery systems:  rationale, advantages, disadvantages.

PDF- ndds-1-2

Session 3

CRDDS: Selection of drug

PDF-  ndds-1 - 3

Session 4

CRDDS: Desired properties of drug candidate

PDF- ndds-1 - 4

Session 5

CRDDS: Desired pharmacokinetic properties

PDF- ndds-1 - 5

Session 6

Approaches to design CRDDS: Dissolution controlled system

PDF- ndds-1 - 6

Session 7

Diffusion controlled system

PPT- ndds-1 - 7

Session 8

Dissolution & Diffusion Controlled Release System, Ion-exchange resins controlled release system

PPT- ndds-1 - 8

Session 9

Classification of CRDDS, Factors influencing the design and act of CRDDS

PDF- ndds-1 - 9

Session 10

Polymers

PDF- ndds-1 - 10

Session 11

Introduction: Microencapsulation

PDF- ndds-2 - 1

Session 12

Methods of microencapsulation-1

PPT- ndds-2 - 2

Session 13

Methods of microencapsulation-2

ndds-2 - 3

Session 14

Methods of microencapsulation-3

PDF- ndds-2 - 4

Session 15

Mucosal Drug Delivery system

PDF- ndds-2 - 5

Session 16

Mucoadhesive drug delivery systems

PDF- ndds-2 - 6

Session 17

Transmucosal permeability buccal delivery
systems

PDF: ndds-2 - 7

Session 18

Structure and design of buccal patches

PDF: ndds-2 - 8

Session 19

Manufacturing Methods of Buccal Patches

PDF: ndds-2 -9

Session 20

Implantable drug delivery systems

PDF: ndds-2 -10

Session 21

Concepts of Implants

ndds-2 -11

Session 22

Introduction to TDDS

PDF: TDDS-1

Session 23

Percutaneous absorption, factors affecting permeation and role of penetration enhancers

PDF: TDDS-2

Session 24

Basic components and formulation approaches of TDDS

PDF: TDDS-3

Session 25

Introduction to GRDDS, Different approaches of GRDDS

PDF:  GRDDS-1

Session 26

Different approaches of GRDDS (Continue)

PDF: GRDDS-2

Session 27

Different approaches of GRDDS (Continue), Application of GRDDS

PDF: GRDDS-3

Session 28

Introduction to nasal route and nasal drug delivery systems

PDF: NASO-1

Session 29

Factors Influencing Nasal Drug Absorption, Nasal Sprays

PDF: NASO-2

Session 30

Characterization of Nasal Spray, Introduction to pulmonary drug delivery

PDF: NASO-3

Session 31

Inhalers, Nebulizers

PDF: NASO-4

Session 32

Introduction to TDDS

PDF: Introduction to TDDS-1

Session 33

Common Approaches of TDDS

PDF: Common Approaches of TDDS-2

Session 34

Strategies of Drug Targeting

PDF: Strategies of Drug Targeting-3

Session 35

Liposomes

PDF: Liposomes-4

Session 36

Niosomes

PDF: Niosomes-5

Session 37

Nanoparticles

PDF: Nanoparticles-6

Session 38

Monoclonal Antibodies

PDF: Monoclonal Antibodies-7

Session 39

Introduction to ODDS

PDF: Introduction to odds-1

Session 40

Anatomy and barriers of eye

PDF: Anatomy and barriers of eye-2

Session 41

Methods to overcome barriers

PDF: Methods to overcome barriers-3

Session 42

Ocular formulations

PDF: Ocular formulations-4

Session 43

Drug delivery systems to posterior segment of the eye

PDF: Drug delivery systems to posterior segment of the eye-5

Session 44

Introduction to IUDs

PDF: Introduction to IUDs-1

Session 45

Anatomy of Uterus

PDF: Anatomy of Uterus-2

Session 46

Mechanisms of action IUD

PDF: Mechanisms of action IUD-3

Session 47

Development of IUD

PDF: Development of IUD-4

Case Studies

Our Main Teachers

Research Area: Novel Drug Delivery Systems Nanocarriers