Fundamentals of Genetics

Teacher

Dr. Praveen Kumar

Category

Core Courses

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Course Name : FUNDAMENTALS OF GENETICS

Code(Credit) : ASPG1101(2-1-0)

Course Objective

  1. To impart knowledge to the students on the ultrastructure of cell and cell organelles

  2. To equip students in both conventional and modern principles of genetics

  3. Applications of principles of genetics in plant breeding for improving agricultural productivity

CO-PO Mapping

COs

Course outcomes

Mapping COs with POs

CO1

Students will be able to understand the basic concepts of the ultrastructure of cell, cell organelles, chromosomes and nucleic acids.

  PO1

CO2

Students could gain acquaintance with the fundamentals of chromosomal and cytoplasmic inheritance.

   PO2

CO3

Students will be able to understanding on sex determination, mutations, chromosomal aberrations and Gene concept: Gene structure, function and regulation

   PO1

CO4

Students will be able to apply the principles of inheritance to plant breeding.

 

   PO4

PO1: Knowledge Enhancement

PO2: Professional Enhancement

PO3: Entrepreneurship Skills

PO4: Communication & Extension Skill

Programme Outcomes

PO1 : Knowledge Enhancement : Demonstrate knowledge and understanding of essential facts, concepts, principles and theories relating to Soil Science, Agronomy, Horticulture, Genetics and Plant Breeding, Plant Pathology, Entomology and other such areas of agriculture.

PO2 : Professional Enhancement : Understanding the value and processes of life-long learning and professional development.

PO3 : Entrepreneurship Skills : Understanding the processes of setting up and managing viable business ventures.

PO4 : Communication & Extension Skills : Developing appropriate communication skills for effective transfer of knowledge and technologies through extension programs.

PO5 : Team Work : Play effective roles in multidisciplinary teams.

PO6 : Educational Leadership : Recognize and meet emerging agriculture challenges of global society in the 21st century and developing leadership and strong linkages in the agro-industrial setup.

PO7 : Data Handling : Collect, analyze and interpret scientific data.

PO8 : Ethics : Apply ethical principles and commit to professional ethics and responsibilities and norms of the scientific practice.

PO9 : Computational Skills : Recognize, analyze problems and plan strategies for their solutions with the help of computer skills.

Course Syllabus

Theory
Pre and Post Mendelian concepts of heredity, Mendelian principles of heredity, Cell division – mitosis, meiosis, Probability and Chi-square.Dominance relationships, gene interaction.
Multiple alleles, pleiotropism and pseudoalleles, Sex determination and sex linkage, sex limited and sex influenced traits, Blood group genetics, Linkage and its estimation, crossing over mechanisms, chromosome mapping. Structural changes in chromosome, Mutation, classification, Methods of inducing mutation & CIB technique, mutagenic agents and induction of mutation. Qualitative & Quantitative traits, Polygenes and continuous variations, multiple factor hypothesis, Epistatic interactions with examples. Cytoplasmic inheritance. Genetic disorders,.Nature, structure & replication of genetic material. Protein synthesis, Transcription and translational mechanism of genetic material, Gene concept: Gene structure, function and regulation, Lac and Trp operons.
Practical
Study of microscope.Study of cell structure. Experiments on monohybrid, dihybrid, trihybrid, test cross and back cross, Experiments on epistatic interactions including test cross and back cross, Practice on mitotic and meiotic cell division, Experiments on probability and Chi-square test. Determination of linkage and cross over analysis (through two point test cross and three point test cross data).Study on sex linked inheritance in Drosophila. Study of models on DNA and RNA structure.

References

1. Pundhan Singh, 2006, Genetics, Kalyani Publishers, Ludhiana
2. Singh, B.D. 2015. Fundamentals of Genetics.Kalyani Publishers, Ludhiana
3. Gupta, P.K.2007. Genetics.Rastogi Publications, Meerut

 

Session Plan

Session 1

Pre Mendelian concepts of heredity

1. Pre & Post Mendelian

L 1

Session 2

Post Mendelian concepts of heredity

Post-mandelain concepts of heredity

Session 3

Mendelian principles of heredity

Mendelian Genetics

mandelain genetics PPT

Session 4

Mendels Laws of Inheritance

Mandels laws of inheritance

Session 5

Session 6

Probability and Chi-Square

X2(Chi-Square)-Probability

Session 7

Qualitative and Quantitative traits

Qualitative Vs Quantitative Characters

Session 8

Session 9

Epistatic Gene interactions

epistasis

Session 10

Multiple alleles

Multiple-alleles

Session 11

Session 12

Crossing Over Mechanism

Crossing Over

Crossing over ppt

Session 13

Curt Stern Experiment on Crossing Over

Cytological basis of crossing over

Session 14

Blood group, Linkage and its estimation
Blood Group System

Blood group genetics

Session 15

Chromosome mapping
Chromosome Maps

Session 16

Cell Cycle-Mitosis

Mitosis

Session 17

Cell Cycle-Meiosis

MEIOSIS

Meiosis figures

Session 18

Mutation & its classification
Mutation-and-classification

PPT MUTATIONS

Session 19

Mutagenic agents and induction of mutation
Mutagens

Session 20

Multiple factor hypothesis
Multiple Factor Hypothesis

Session 21

Session 22

Sex Determination 2

sex-determination-10-18

Session 23

Cytoplsmic Inheritance
Cytoplasmic-inheritence

Session 24

Nature, structure of genetic material
Nature- Structure of DNA

Session 25

Replication of genetic material and Central Dogma
Replication of DNA and central dogma

Session 28

Structure of mRNA, Nucleotides

structure of mRNA and nucleotides and DNA

Session 29

Transcription

Transcription

Session 30

Translational mechanism of genetic material and Protein synthesis
Translation

Session 31

Gene concept: Gene structure, function and regulation, Lac and Trp operan
Gene concept

tryptophan operon

Session 32

Genetic diseases
genetic disorders

Practice-I

Study of Microscope and its parts

Microscopy

Practice-2

Problems on Magnification and Resolving Power

Problems on Resolving Power

Practice-3

Study of cell Ultrastructure-I (Cell wall, Plasma membrane, Cell wall, Cytoplsam, Endoplasmic Reticulum)

Cell Ultrastructure - I

Practice-4

Study of cell Ultrastructure-I (Nucleus, Ribosome, Mitochondria, Lysosome, Chloroplast, Peroxisome)

Cell Ultrastructure 11

Practice-5

Experiments on Monohybrid, Dihybrid, Trihybrid crosses

Experiments on Mono-Di-Tri-Hybrid crosses

Practice-6

Experiments on  Multiple alleles

Experiments on Multiple alleles

Practice-7

Experiments on Epistatic Gene Interactions

Epistatic Gene Interactions

Practice-8

Practice on Mitotic Cell Division

Mitotic Cell Division

Practice-9

Practice on Meiotic Cell Division

Meiotic studies

Practice-10

Experiment on Chi-square test and Probability

Chi-Square and Prabability

Practice-11

Determination of Linkage and Crossing Over (Estimation of Two-Point test cross)

Problems on two-point test cross

Practice-12

Determination of Linkage and Crossing Over (Estimation of Three-Point test cross)

Problems on Three point Test Cross

Practice-13

Study of Sex linked inheritence in Drosophila

Sex linked inheritance in Drosophila

Practice-14

Study of Models on DNA

Studying DNA Models

Practice-15

Study of Models on Nucleotides

Models of Nucleotides and RNA

Practice-16

Study of Models on RNA

Models of Nucleotides and RNA

Question Bank

Question Bank

PO1 PO2 P03 P04 P05 P06 P07 P08 P09
CO1 3.00 3.00 3.00 2.00 2.00 1.00 2.00 2.00
CO2 3.00 3.00 3.00 2.00 2.00 1.00 1.00 2.00 1.00
CO3 3.00 3.00 3.00 2.00 2.00 2.00 1.00 2.00 2.00
CO4 3.00 3.00 3.00 2.00 2.00 2.00 1.00 2.00 1.00

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Dr. Praveen Kumar

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