Pharmacognosy and Phytochemistry-II

Teacher

ABHISEK SAHU

Category

Core Courses

Course Attendees

Still no participant

Course Reviews

Still no reviews

Course Name : Pharmacognosy & Phytochemistry

Code(Credit) : BPHT3104(4-0-0)

Course Objectives:

The main purpose of subject is to impart the students the knowledge of how the secondary metabolites are produced in the crude drugs, how to isolate and identify and produce them industrially. Also this subject involves the study of producing the plants and phytochemicals through plant tissue culture, drug interactions and basic principles of traditional system of medicine.

Course Outcomes

CO Statement Mapping with POs
CO-1 To know the modern extraction techniques, characterization and identification of the herbal drugs and phytoconstituents.  PO1, PO2, PO8
CO-2 To understand the preparation and development of herbal formulation. PO1, PO6, PO9
CO-3 To understand the herbal drug interaction. PO1, PO2, PO8
CO-4 To carryout isolation and identification of phytoconstituents. PO1, PO3, PO6, PO8
CO-5 To get professional, practical skills in extraction isolation and phytochemical analysis of natural products. PO1, PO2, PO6

Course Syllabus

Module-I
Metabolic pathways in higher plants and their determination
a) Brief study of basic metabolic pathways and formation of different secondary metabolites
through these pathways- Shikimic acid pathway, Acetate pathways and Amino acid pathway.
b) Study of utilization of radioactive isotopes in the investigation of Biogenetic studies.
Module II
General introduction, composition, chemistry & chemical classes, biosources, therapeutic
uses and commercial applications of following
secondary metabolites:
Alkaloids: Vinca, Rauwolfia, Belladonna, Opium,
Phenylpropanoids and Flavonoids: Lignans, Tea, Ruta
Steroids, Cardiac Glycosides & Triterpenoids: Liquorice, Dioscorea, Digitalis
Volatile oils: Mentha, Clove, Cinnamon, Fennel, Coriander,
Tannins: Catechu, Pterocarpus
Resins: Benzoin, Guggul, Ginger, Asafoetida, Myrrh, Colophony
Glycosides: Senna, Aloes, Bitter Almond
Iridoids, Other terpenoids & Naphthaquinones: Gentian, Artemisia, taxus, carotenoids
Module III
Isolation, Identification and Analysis of Phytoconstituents
a) Terpenoids: Menthol, Citral, Artemisin
b) Glycosides: Glycyrhetinic acid & Rutin
c) Alkaloids: Atropine,Quinine,Reserpine,Caffeine
d) Resins: Podophyllotoxin, Curcumin
Module IV
Industrial production, estimation and utilization of the following phytoconstituents:
Forskolin, Sennoside, Artemisinin, Diosgenin, Digoxin, Atropine, Podophyllotoxin, Caffeine,
Taxol, Vincristine and Vinblastine
Module V
Basics of Phytochemistry
Modern methods of extraction, application of latest techniques like Spectroscopy,
chromatography and electrophoresis in the isolation, purification and identification of crude
drugs.

References:

1. W.C.Evans, Trease and Evans Pharmacognosy, 16th edition, W.B. Sounders & Co.,
London, 2009.
2. Mohammad Ali. Pharmacognosy and Phytochemistry, CBS Publishers &
Distribution, New Delhi.
3. Text book of Pharmacognosy by C.K. Kokate, Purohit, Gokhlae (2007), 37th Edition,
Nirali Prakashan, New Delhi.
4. Herbal drug industry by R.D. Choudhary (1996), Ist Edn, Eastern Publisher, New
Delhi.
5. Essentials of Pharmacognosy, Dr.SH.Ansari, IInd edition, Birla publications, New
Delhi, 2007
6. Herbal Cosmetics by H.Pande, Asia Pacific Business press, Inc, New Delhi.
7. A.N. Kalia, Textbook of Industrial Pharmacognosy, CBS Publishers, New Delhi,
2005.
8. R Endress, Plant cell Biotechnology, Springer-Verlag, Berlin, 1994.
9. Pharmacognosy & Pharmacobiotechnology. James Bobbers, Marilyn KS, VE Tylor.
10. The formulation and preparation of cosmetic, fragrances and flavours.
11. Remington’s Pharmaceutical sciences.
12. Text Book of Biotechnology by Vyas and Dixit.
13. Text Book of Biotechnology by R.C. Dubey.

Session 3

Acetate pathways

https://www.youtube.com/watch?v=YRdKQ_zAxm0

Session 6

Amino acid pathway

https://www.youtube.com/watch?v=ZT4DzfIRMeQ

Session  7

Amino acid pathways

https://www.youtube.com/watch?v=0J-z25R75rE

Session 8

Study of utilization of radioactive isotopes in the investigation of Biogenetic studies.

 

https://www.youtube.com/watch?v=WsigAEO4kR8

Session 9

Study of utilization of radioactive isotopes in the investigation of Biogenetic studies.

https://www.youtube.com/watch?v=LKaIMiWPhoY

Session 10

General introduction, composition, chemistry & chemical classes, biosources, therapeutic uses and commercial applications of Alkaloids: Vinca, Belladonna,

https://www.youtube.com/watch?v=cCNMkZnjtQE

Session  11

Rauwolfia & opium

https://www.youtube.com/watch?v=brpp1yWGCBQ

Session 12

Phenylpropanoids and Flavonoids: Lignans, Tea, Ruta

https://www.youtube.com/watch?v=XysR5RTl7Zs

Session 16

Volatile oils: Mentha, Clove

https://www.youtube.com/watch?v=zInTCSOfRks

Session 17

Cinnamon, coriander

https://www.youtube.com/watch?v=pTTWapSsckk

Session 19

Tannins: Catechu, Pterocarpus

https://www.youtube.com/watch?v=JPDjFfB9Qn4

Session 20

Resins: Benzoin

https://www.youtube.com/watch?v=iDL8lE4MtgI

Session 22

Ginger, Asafoetida

https://www.youtube.com/watch?v=rdhLj0S-E_w

Session 25

Senna and bitter almond

 

https://www.youtube.com/watch?v=n-DqP4esUPk

Session 27

Isolation, Identification and Analysis of Phytoconstituents
a) Terpenoids: Menthol, Citral, Artemisin

https://www.youtube.com/watch?v=WzXUaJqG0YE

Session 28

Isolation, Identification and Analysis of Phytoconstituents Glycosides: Glycyrhetinic acid & Rutin

https://www.youtube.com/watch?v=qJT4GfBgeyE

Session 29

Isolation, Identification and Analysis of Phytoconstituents

https://www.youtube.com/watch?v=sSO6fLO7_UA

Alkaloids: Atropine,Quinine,Reserpine,Caffeine

Session 30

Isolation, Identification and Analysis of Phytoconstituents

Resins: Podophyllotoxin, Curcumin

https://www.youtube.com/watch?v=DN0HbpxAURo

Session 31

Industrial production, estimation and utilization of the following phytoconstituents:
Sennoside

https://www.youtube.com/watch?v=ezDhkP37pec

Session

Session 32

Industrial production, estimation and utilization of the following phytoconstituents:Forskolin
https://www.youtube.com/watch?v=eoWtqAqdsTU

Session 33

Industrial production, estimation and utilization of the following phytoconstituents: Caffeine

https://www.youtube.com/watch?v=2_0eT0dP6yc

Session 34

Industrial production, estimation and utilization of the following phytoconstituents: Vincristine and Vinblastine

https://www.youtube.com/watch?v=zqW6BTr3vQo

Session 35

Industrial production, estimation and utilization of the following phytoconstituents: Taxol,

https://www.youtube.com/watch?v=IlT6PRWSvhw

Session 36

Industrial production, estimation and utilization of the following phytoconstituents:Digoxin

https://www.youtube.com/watch?v=XxKhqGWJd9U

Session 37

Industrial production, estimation and utilization of the following phytoconstituents : Diosgenin

https://www.youtube.com/watch?v=x2prGiTtfa0

Session 38

Industrial production, estimation and utilization of the following phytoconstituents: Artemisinin,

https://www.youtube.com/watch?v=xI4bBtjsMRY

Session

Session

Case Studies

Case Studies

Our Main Teachers