Cell Biology CUTM2605(3-0-1)

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Venkata Kalyan Kankanala

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Course Name : Cell Biology

Code(Credit) : CUTM2605(3-0-1)

Course Objectives

  • To make the student understand all type of cells and cellular components, and how cell works in healthy and diseased states

Learning Outcomes

  • Students will understand:
  • The structures and purposes of basic components of prokaryotic and eukaryotic cells.
  • How the cellular components are organized and perform specific functions.
  • The cellular components underlying mitotic and meiotic cell division.
  • The cellular abnormalities and variations

Course Syllabus

Module- 1 (11 Hrs)

Overview of Cells; Cell theory; Prokaryotic and Eukaryotic cells; Virus; Viroids; Mycoplasma; Prions.

 

Module- 2 (10 Hrs)

Plasma Membrane: Various models of plasma membrane structure; Transport across membranes: Active and Passive transport, Facilitated Transport; Cell junctions: Tight junctions, Gap junctions, Desmosomes, Hemi desmosomes.

 

Module- 3 (6 Hrs)

Endomembrane System: Structure and Functions of Endoplasmic Reticulum, Golgi apparatus, Lysosomes.

 

Module- 4 (8 Hrs)

Mitochondria: Structure and function, Semi-autonomous nature, Endosymbiotic hypothesis, Chemiosmotic hypothesis, Mitochondrial electron transport chain; Peroxisomes: structure and function.

 

Module- 5 (10 Hrs)

Cytoskeleton: Structure and Functions: Microtubules, Microfilaments and Intermediate filaments; Nucleus: Structure of Nucleus: Nuclear envelope, nuclear pore complex, Nucleolus, Chromatin: Euchromatin and Heterochromatin and packaging (nucleosome).

 

Module 6

Cell Division and Cell cycle: Mitosis, Meiosis; Regulation of cell cycle.

 

Module- 7 (10 Hrs)

Cell Signalling: Overview of cell signalling, signalling molecules and receptors, GPCR, Second messengers, Role of second messenger (cAMP) in cell signalling, Activation of gene transcription by GPCR.

 

Text Books:

  1. Karp, G. (2010). Cell and Molecular Biology: Concepts and Experiments. VI John Wiley and Sons. Inc.
  2. De Robertis, E.D.P. and De Robertis, E.M.F. (2006). Cell and Molecular Biology. VIII Edition. Lippincott Williams and Wilkins

 

Reference Books:

  1. Cooper, G.M. and Hausman, R.E. (2009). The Cell: A Molecular Approach. V ASM Press and Sunderland, Washington, D.C.; Sinauer Associates, MA.
  2. Becker, W.M., Kleinsmith, L.J., Hardin. J. and Bertoni, G. P. (2009). The World of the Cell. VII Edition. Pearson Benjamin Cummings Publishing, San
  3. Bruce Albert, Bray Dennis, Levis Julian, Raff Martin, Roberts Keith and Watson James (2008). Molecular Biology of the Cell, V Edition, Garland publishing Inc., New York and London

Session Plan

Session 1

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Session 2

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Venkata Kalyan Kankanala