Certificate in Supercritical Carbon Dioxide Plant Operation


Pradipta Banerjee, Ph.D.


Certificate Courses

Course Attendees

Still no participant

Course Reviews

Still no reviews

Course Name: Certificate in Super Critical Carbon Dioxide Plant Operation

Code (Credits): ( 1+2+1)

Course Description

  1. Short description: Supercritical fluid extraction (SFE) is the process of separating one component (the extractant) from another (the matrix) using supercritical fluids as the extracting solvent. It is one of the most popular green extraction widely accepted in the industries. This certificate course aims to provide the trainees a hands-on practical experience of this extraction method along with the most updated knowledge on the SCFE technique.
  1. Eligibility: B.Sc. Chemistry/Life Sciences; M.Sc. in any branch of Life Sciences/M.Sc. Chemistry; ITI
  2. Prerequisite: Basic knowledge of organic chemistry
  3. Duration of the course: One-month online theory class and 50 hours practical in PKD Campus or collaborative work with our Industrial Partners.
  4. Key highlights
  • Faculty: Dr. Preetha Bhadra, Dr. Rosy Mallik, Dr. Pradipta Banerjee
  • The certificate will be issued jointly by Gram Tarang Foods Pvt. Ltd. & Centurion University of Technology and Management.
  • Job Opportunity: In Pharmaceutical, Nutraceutical, Cosmetics Industry.
  • Contact with Industry Personnel: Mr. Babu Shankar, MD, Gram Tarang Foods Pvt. Ltd.; md@gramtarangfoods.in

Course Objectives

  • The trainees will get hands-on experience in the SCF extraction method.
  • The course curriculum aims towards acquiring technical skills.

Learning Outcomes


On completion of this course, students will be able to

  • Run the supercritical fluid extraction independently
  • Troubleshoot problems related to the extraction and can engage themselves in research and development to get scientific publications and patents

Course Syllabus

Module - I

Introduction to supercritical fluids (SCFs): Supercritical fluids and their properties, Examples of SCFs, Chemistry of SCFs

Module - II

Instrumentation: What are the different parts of SCF extraction plant, identification and learning the use of different parts of the SCF extraction unit, general maintenance and cleaning of the unit

Practice 1:

Visit to SCF extraction Unit of PKD Campus and hands on training on the instrumentation from the experts/engineers working there.

Module – III

Industrial application: Uses of SCF extraction in different industries (pharma, cosmetics, nutraceutical), SCF extraction is favoured over other conventional techniques, Why this technique is known as Green extraction technique.

Practice 2:

  • Exposure visit to Gram Tarang Foods Pvt. Ltd. and other industrial partners.
  • Real time interaction with extraction experts

Module – IV

Methodology: Raw materials for SCF extraction process, sample preparation, calculation of percentage yield of desired product

Practice 3:

  • Collection of raw materials
  • Sample preparation
  • Extraction of ginger oil
  • Extraction of turmeric oil
  • Extraction of marigold
  • Extraction from tulsi leaf
  • Calculation of percentage yield
  • Hands on training to troubleshoot different problems related to SCF extraction

Module – V

Modifiers: What are modifiers, role of modifiers in SCF extraction, organic modifier, food grade modifier

Practice 4:

Assignment (Any one)

  • Modifier Effects on Supercritical CO2 Extraction Efficiency
  • Modifier Effects in the Supercritical Fluid Extraction of Solutes from Plant Materials

Module – VI

Purification of extract: A brief idea of downstream process of the SCF extracts, methods of purification of organic molecules, identification of organic molecules.

Practice 5:

  • Freeze Drying
  • Column chromatography
  • Paper chromatography
  • HPLC (optional)

Module – VII

Importance of SCF extraction: advantages of SCF extraction over other conventional techniques, limitations of SCF extraction, troubleshoot

Practice 6:

  • Hands on training by GTF Pvt. Ltd. Experts on troubleshooting different probable problems that may occur while operating the SCF extraction unit
  • Doubt clearing about the operation of SCF extraction process

Text Book:

Supercritical Carbon Dioxide Extraction Handbook (Publisher: Scholars’ Press) By P. Banerjee, R. Mallik and S. Maji

Reference Books:

  1. Natural Extracts Using Supercritical Carbon Dioxide By Mamata Mukhopadhyay
  2. Supercritical Fluid Methods and Protocols By Tony Clifford (Publisher: Humana Press)
  3. Supercritical Fluid Extraction and Its Use in Chromatographic Sample Preparation (Publisher: Springer, Netherlands).

Session Plan

Session 1

Introduction to Supercritical Fluid

Introduction to SCF extraction
Lecture 1, 2_SCFE

Session 2

Principle of Supercritical Fluid Extraction

Principle of SCF extraction

Lecture 1, 2_SCFE 

Session 3

Instrumentation of Supercritical Fluid Extractor


Lecture 3_ SCFE 

Session 4

Industrial Application of SCFE

Industrial Application of SCF extraction

Lecture 4, 8_SCFE 

Session 5

Raw materials for SCFE, Sample preparation, calculation of percentage yield of the desired product

Raw materials required for SCFE

Lecture 5_SCFE 

Session 6

Modifiers for SCFE

Modifier for SCF extraction

Lecture 6_SCFE 

Session 7

Purification of the extracted sample

Lecture 7_SCFE

Session 8

Advantages, Limitations of SCFE

Lecture 4, 8_SCFE


15% marks for two assignments

20% marks for one internal test

10% marks for one quiz test

30% marks for two practical tests

20% marks for final exam

5% marks for attendance

List of Projects/ papers/jobs/products linked with SCF extraction Certificate Course

  1. Extraction of bioactive compounds from plant sources (marigold, turmeric, ginger, black pepper, tulsi, etc.)
  2. Extraction of antioxidants from medicinal plants
  3. Purification of molecules from extracts
  4. Research papers & patents (process patent or product patent)
  5. Short term projects in collaboration with Gram Tarang Foods and different other industries/laboratories that will help the trainee to build a career in the fields of Pharmaceutical, Nutraceutical, Cosmetic Chemistry, Biochemistry.

Our Main Teachers

Present Position Assistant Professor, Dept. of Biochemistry and Plant Physiology, MSSSoA, Centurion University of Technology & Management, Odisha, India Mobile: 9330492088 , E-mail: pradipta.banerjee@cutm.ac.in Education Bachelor of Science (Biotechnology), PES College, Bangalore University, Karnataka, India Master of Science (Biochemistry), Vidya Sagar University, West Bengal, India Ph.D. (Soil Sc. & Agri. Chemistry), Visva Bharati University, Birbhum, […]

  Assistant Professor Centurion University of Technology and Management Odisha, India   Teaching  Organic Chemistry Synthetic methods  Stereochemistry  Natural products Research areas/interests  Synthetic methodology  Natural product synthesis  Organocatalysis About Me   Ph.D in Synthetic organic chemistry from National Chemical Laboratory, Pune Research area: Carbohydrate chemistry, Transition metal catalysis, Methodology and total synthesis. Post-doctoral research: Central […]