CUTM1647 Pharmacology and Pharmaceutical Drug Analysis

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Manisha Panda

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COURSE OBJECTIVE

This course serves as an introduction to the basic principles of forensic pharmacology. Students will learn key concepts that are important to understanding drug actions, including principles of pharmacokinetics (e.g., absorption, distribution, metabolism and excretion of drugs) as well as the physiological and cellular basis for a host of diverse drug actions.

COURSE OUTCOME

SNO DESCRIPTION PO MAPPING
CO1 Understand about the drug, factors, bioavailability, and responses of drugs. PO6, PO9, PO12
CO2 Understanding the different agents of drugs, designer drugs and NDPS substances. PO6, PO9, PO12, PO15
CO3 Analysis of drugs and agents. PO6, PO9, PO12,PO15
CO4 Qualitative and quantitative analysis of various chemicals. PO6, PO9, PO12, PO15
CO5 Instrumental analysis of various chemicals. PO6, PO9, PO12, PO15

UNIT- I   Basic Principles of Pharmacology
Introduction to Pharmacology
Pharmacopoeias IP, USP, EP
Drug & Drug Receptor mechanisms
Pharmacodynamics
Factor affecting the effects of Drug
Post mortem redistribution

UNIT- II   Pharmacokinetics
L-ADME
Bioavailability and Bioaccumulation
Dose response relationship
Drug Interactions like Agonism, Antagonism, Addition, Synergism, Potentiation
Adverse drug reactions and pharmacogenetics
Drug concentration and pharmacological response
Drug dependence and drug abuse

UNIT- III     Pharmacology and Pharmaceutical Analysis
Aliphatic alcohols
General and local Anesthetics
CNS Stimulants
Sedative, Hypnotics and Pharmacotherapy of sleep disorders
Drugs effective in convulsive disorders

UNIT- IV       Pharmacology and Pharmaceutical Analysis
Antipsychotic Agents
Antidepressant drugs
Antiseizure Drugs
Drugs of Abuse
Tranquillizers
Narcotic Drugs and Psychotropic Substance
Schedule and Nonscheduled Drugs
Designer Drugs
Doping Drugs
Hallucinogens

UNIT- V     Pharmacology and Pharmaceutical Analysis
Chemotherapeutic Drugs
Antibacterial
Antifungal agents
Antiviral agents
Antiprotozoal Drugs
Disinfectants, Antiseptics and Sterilants

REFERENCE BOOKS

Klaassen, C. D.,:Casarett and Doull’s Toxicology: The Basic Sciences of Poisons, 5th ed, McGraw-Hill, 1995.
Moffat, A.C. : Osselton, D. M. Widdop, B. : Clarke’s Analysis of Drugs and Poisons in Pharmaceuticals, body fluids and postmortem material, 3rd ed., Pharmaceutical Press2004.

Bogusz, M. J.,: Hand Book of Analytical Separations, Vol. 2: Forensic Sciences, 1st ed., Elsevier Sciences ,2000.
Siegel, J.A., Saukko, P. J., Knupfer, G.,: Encyclopedia of Forensic Sciencess (Vol3), Academic Press, 2000.
Rang, P.H., Dale, M.M., Ritter, M.J.: Pharmacology, 4th ed., Harcourt/Churchill Livingstone, 2000.
Paranjape, H.M., Bothara, G.K., Jain, M.M.: Fundamentals of Pharmacology, 1st ed., Nirali Prakashan, 1990.

Session 1

Introduction to Pharmacology, Pharmacopoeias IP, USP, EP

pharmaceutical analysis- pharmacopoeia pdf

Session 2

Drug & Drug Receptor mechanisms, Pharmacodynamics

Drug_-_Receptor_Interactions

Session 6

Bioavailability and Bioaccumulation

Bioavailibility and bioconcentration

Session 7

Dose response relationship
Drug Interactions like Agonism, Antagonism, Addition, Synergism, Potentiation

drug interactions

Session 8

Adverse drug reactions and pharmacogenetics

Adverse drug reactions

Pharmacogenetics

Session 9

Drug concentration and pharmacological response
Drug dependence and drug abuse

dose-response-relationships

Session 10

Aliphatic alcohols

Session 11

General and local anaesthetics

General & Local Anesthetics

Session 12

CNS Stimulants

CNS Stimulants

Session 13

Sedative, Hypnotics and Pharmacotherapy of sleep disorders

Sedative, Hypnotics and Pharmacotherapy of sleep disorders

Session 14

Drugs effective in convulsive disorders

Anticonvulsant drugs

Session 15

Antipsychotic Agents

Antipsychotic drugs

Session 16

Antidepressant drugs

Antidepressant drugs

Session 17

Antiseizure Drugs

Antiseizure drugs

Session 18

Drugs of Abuse

Session 19

Tranquillizers

Tranquilizers

Session 20

Narcotic Drugs and Psychotropic Substances

NDPS

Session 21

Schedule and Nonscheduled Drugs

Session 24

Hallucinogens

Hallucinogen

Session 23

Doping Drugs

Doping drugs

Session 26

Antibacterial Drugs

Antibacterial drugs

Session 27

Antifungal agents
Antiviral agents

Antifungal drugs

Antiviral drugs

Session 28

Antiprotozoal Drugs

1343_antiprotozoal%20agents.pdf

Session 29

Disinfectants, Antiseptics and Sterilants

https://byjus.com/chemistry/antiseptics-and-disinfectants/

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