CUTM2900 FUNDAMENTALS OF FORENSIC TOXICOLOGY

Teacher

Manisha Panda

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Course Credit: 3-0-0

Course Objectives:

1. To help students learn basic principles of toxicology.
2. To study and understand concepts of mechanism of toxicity.
3. To learn the concepts of toxicological examination.

Course Outcomes

On completion of this course, the successful students should be able to:

S.NO DESCRIPTION PO MAPPING
Understand the history, scope and significance of forensic toxicology, including the medico-legal aspects of poisoning, relevant laws and the roles of nodal agencies and stakeholders. PO1, PO2, PO12

2.

Learn the standard formats for preparation of autopsy and laboratory reports in forensic toxicology. PO1, PO2, PO3, PO8

3.

Analyze the protocols and procedures for the collection and preservation of biological and non-biological samples in accordance with national and international guidelines.  PO1, PO2, PO3, PO4

4.

Understand the potential hazards associated with sample collection and the importance of safety measures in handling toxicological samples. PO1, PO2, PO3, PO4

5.

Acquire a comprehensive understanding of the methodologies and techniques involved in the extraction, detection and quantification of poisons. PO1, PO2, PO3, PO4, PO12

Module-1 Basics of Forensic Toxicology 

History, Scope and Significance, Crime scene involving poisons, medico legal aspects of poisoning, Laws related to poisons, nodal agencies and stake holders in forensic toxicology, nature of forensic toxicological examinations, Roles and Responsibilities of forensic toxicologists, drug paraphernalia, poisoning management, Format of autopsy report and laboratory report, expert witness testimony.

Module-2  Collection and Preservation

Biological and non-biological samples, classes of matrices, National and International guidelines of toxicological sample collection, post-mortem examination, types of viscera, viscera collection and preservation, types of preservatives, types of containers, self-life of samples, Safety measures of toxicological samples handling, Personal Protective Equipment (PPEs).

Module-3 Extraction and Examination

Extraction of poisons from biological and non-biological samples, Methods of Extraction, Liquid-Liquid extraction, extraction methods for acidic, basic and neutral poisons, extraction of volatile and non-volatile poisons, extraction of plant poisons, common methods of poison detection, chemical tests, Instrumental methods for toxicological examination, Toxicological analysis of decomposed material and body remains, challenges in forensic toxicological examination.

Reference Books:
1. Modi JS: Medical Jurisprudence and Toxicology
2. Taylor: Medical Jurisprudence
3. Parikh CK: Medical Jurisprudence and Toxicology
4. Keith Simpsen & Bernard Knight: Forensic Medicine
5. Poison, CJ, DJ Gee, B. Knight: Forensic Medicine
6. Reddy: Forensic Medicine
7. Laboratory Procedure Manual- Forensic Toxicology, DFS, MHA, New Delhi
8. Pharmacology and Therapeutics-Bhandarkar & Satoskar
9. Medical Pharmacology- Tripathy
10. Essentials of Toxicology- Ellenhorn

Session Plan

Session 1

History, Scope and Significance of Toxicology

HISTORY, SCOPE AND SIGNIFICANCE OF TOXICOLOGY

Session 2

Crime scene involving poisons

Crime scene involving poisons

Session 3

Medico-legal aspects of poisoning

Session 4

Laws related to poisons

Session 5

Nodal agencies and stake holders in forensic toxicology

Nodal agencies and stakeholders in forensic toxicology

Session 6

Nature of forensic toxicological examinations

Nature of forensic toxicological examination

Session 7

Roles and Responsibilities of forensic toxicologists

Roles and responsibilities of forensic toxicologists

Session 8

Drug paraphernalia

Drug paraphernalia

Session 9

Poisoning management

Session 10

Format of autopsy report and laboratory report

Autopsy Report Format

Session 11

Expert witness testimony

Expert witness

Session 12

Biological and non-biological samples

Biological and non-biological samples

Session 13

Classes of matrices

National and International guidelines of toxicological sample collection

Guidelines for sample collection

Session 14

Post-mortem examination

Postmortem examination

Session 15

Types of viscera

Types of viscera

Viscera collection and preservation

Viscera collection and preservation

Session 16

Types of preservatives

Types of containers

Types of preservatives and containers

Session 17

Shelf-life of samples

Shelf life of samples

Safety measures of toxicological samples handling

Safety measures of toxicological examination

Session 18

Personal Protective Equipment (PPEs)

PPE

Session 19

Extraction of poisons from biological and non-biological samples

Session 20

Methods of Extraction

Session 21

Liquid-Liquid extraction

Liquid-liquid extraction

Extraction methods for acidic poisons

Acidic poisons

Session 22

Extraction methods for basic poisons

Basic poisons

Session 23

Extraction methods for neutral poisons

Session 24

Extraction methods for volatile poisons

Session 25

Extraction methods for non-volatile poisons

Session 26

Extraction methods for plant poisons

Session 27

common methods of poison detection- chemical methods

Session 28

Instrumental methods for toxicological examination

Instrumental analysis

Session 29

Toxicological analysis of decomposed material and body remains

Toxicological analysis of decomposed remains

Session 30

Challenges in forensic toxicological examination

Challenges in forensic toxicological examination

Our Main Teachers

Manisha Panda

Assistant Professor
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