Course Credit: 3-0-0
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Course Credit: 3-0-0
Course Objectives:
1. To help students learn basic principles of toxicology.
2. To study and understand concepts of mechanism of toxicity.
3. To learn the concepts of toxicological examination.
Course Outcomes
On completion of this course, the successful students should be able to:
S.NO | DESCRIPTION | PO MAPPING |
|
Understand the history, scope and significance of forensic toxicology, including the medico-legal aspects of poisoning, relevant laws and the roles of nodal agencies and stakeholders. | PO1, PO2, PO12 |
2. |
Learn the standard formats for preparation of autopsy and laboratory reports in forensic toxicology. | PO1, PO2, PO3, PO8 |
3. |
Analyze the protocols and procedures for the collection and preservation of biological and non-biological samples in accordance with national and international guidelines. | PO1, PO2, PO3, PO4 |
4. |
Understand the potential hazards associated with sample collection and the importance of safety measures in handling toxicological samples. | PO1, PO2, PO3, PO4 |
5. |
Acquire a comprehensive understanding of the methodologies and techniques involved in the extraction, detection and quantification of poisons. | PO1, PO2, PO3, PO4, PO12 |
Module-1 Basics of Forensic Toxicology
History, Scope and Significance, Crime scene involving poisons, medico legal aspects of poisoning, Laws related to poisons, nodal agencies and stake holders in forensic toxicology, nature of forensic toxicological examinations, Roles and Responsibilities of forensic toxicologists, drug paraphernalia, poisoning management, Format of autopsy report and laboratory report, expert witness testimony.
Module-2 Collection and Preservation
Biological and non-biological samples, classes of matrices, National and International guidelines of toxicological sample collection, post-mortem examination, types of viscera, viscera collection and preservation, types of preservatives, types of containers, self-life of samples, Safety measures of toxicological samples handling, Personal Protective Equipment (PPEs).
Module-3 Extraction and Examination
Extraction of poisons from biological and non-biological samples, Methods of Extraction, Liquid-Liquid extraction, extraction methods for acidic, basic and neutral poisons, extraction of volatile and non-volatile poisons, extraction of plant poisons, common methods of poison detection, chemical tests, Instrumental methods for toxicological examination, Toxicological analysis of decomposed material and body remains, challenges in forensic toxicological examination.
Reference Books:
1. Modi JS: Medical Jurisprudence and Toxicology
2. Taylor: Medical Jurisprudence
3. Parikh CK: Medical Jurisprudence and Toxicology
4. Keith Simpsen & Bernard Knight: Forensic Medicine
5. Poison, CJ, DJ Gee, B. Knight: Forensic Medicine
6. Reddy: Forensic Medicine
7. Laboratory Procedure Manual- Forensic Toxicology, DFS, MHA, New Delhi
8. Pharmacology and Therapeutics-Bhandarkar & Satoskar
9. Medical Pharmacology- Tripathy
10. Essentials of Toxicology- Ellenhorn
Session Plan
Session 1
History, Scope and Significance of Toxicology
Session 3
Medico-legal aspects of poisoning
Session 4
Laws related to poisons
Session 5
Nodal agencies and stake holders in forensic toxicology
Session 6
Nature of forensic toxicological examinations
Session 7
Roles and Responsibilities of forensic toxicologists
Session 9
Poisoning management
Session 13
Classes of matrices
National and International guidelines of toxicological sample collection
Session 15
Types of viscera
Viscera collection and preservation
Session 17
Shelf-life of samples
Safety measures of toxicological samples handling
Session 19
Extraction of poisons from biological and non-biological samples
Session 20
Methods of Extraction
Session 21
Liquid-Liquid extraction
Extraction methods for acidic poisons
Session 23
Extraction methods for neutral poisons
Session 24
Extraction methods for volatile poisons
Session 25
Extraction methods for non-volatile poisons
Session 26
Extraction methods for plant poisons
Session 27
common methods of poison detection- chemical methods
Session 29
Toxicological analysis of decomposed material and body remains
Session 30
Challenges in forensic toxicological examination