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Theory
General Toxicology:Definitions, Branches of Toxicology, Historical developments, Classification of poison. Types of poisoning- Toxicity testing - Chronocity factor, Untoward effects, Common causes, Diagnosis of poisoning, Factors modifying toxicity, Toxicokinetics, Toxicodynamics, General approaches to diagnosis and treatment of poisoning.
Systemic Toxicology:Toxicity caused by metal and non-metals, Phytotoxins- Toxic principles of various alkaloids and toxic plants, Drug toxicity and toxicity caused by agrochemicals. Mycotoxins, Bacterial toxins. Collections and dispatch of specimens in Toxicological cases, Toxicity of drugs in Aquaculture: Maximum Residual Limits (MRL) of various drugs and chemicals in fish Metabolism of toxic substances by aquatic organisms. Endocrine Disrupture Chemicals (EDC)
Practicals
Detection of heavy metal poisoning. Spot tests for metals. Group reaction for metals- Arsenic, Antimony, Lead (Pb), Mercury (Hg), Zinc (Zn), Barium (Ba), Iron (Fe3+ ), Copper (Cu), Ammonia (ammonium ions) NH4+ Chloride (Cl-), Phosphate (P04) Sulphate (S04 ) Flouride (Fl-), Qualitative detection of Nitrite and Nitrate, Detection of hydrocyanic acid, Detection and Estimation of Mycotoxins, Test for detection of alkaloids, Estimation of LD5O and ED5O Demonstration of drug toxicity.
Suggested Readings-
Fish Pharmacology and Toxicology – Govind Pandey
Fish Pathology -Ronald J. Roberts
PDF link: FT ppt-8
Video link:Treatment of poison animal
Theory 11: Drug toxicity and toxicity caused by agrochemicals
PDF link: FT ppt-11
Video link:Drug toxicity
Theory 12: Toxicity caused by Agrochemicals
PDF link: FT ppt-12
Video link:Toxicity caused by Agrochemicals
Theory 13: Arsenic & Mercury: Toxicity effects
PDF link: FT ppt-13
Video link:Arsenic & Mercury: Toxicity effects
PDF link: FT ppt-16
Video link:Sample collection
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