Fish Toxicology


Tasok Leya


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Course Name : Fish Toxicology

Code(Credit) : FSHM 3105(1-1-0)

Course Objectives

  • To learn the basic principles of general toxicology, branches of toxicology, classification of poison and diagnosis of poisoning.To learn toxicokinetics, toxicodynamics, systemic toxicology and different types of toxins: phytotoxins, mycotoxins, bacterial toxins.

Learning Outcomes

  • Demonstrate an understanding of the processes involved in absorption, distribution, metabolism and excretion of toxicants, including an understanding of the toxicokinetic behavior of toxicants in fish.Identify relationships between chemical exposure and effects on physiological systems and design strategies for study of dose-response relationships.Demonstrate an understanding of target organ toxicity involving the following organ systems: liver, kidney, blood, skin, reproductive systems.

Course Syllabus

General Toxicology:Definitions, Branches of Toxicology, Historical developments, Classification of poison. Types of poisoning- Toxicity testing - Chronocity factor, Untoward effects, Common causes, Diagnosis of poisoning, Factors modifying toxicity, Toxicokinetics, Toxicodynamics, General approaches to diagnosis and treatment of poisoning.
Systemic Toxicology:Toxicity caused by metal and non-metals, Phytotoxins- Toxic principles of various alkaloids and toxic plants, Drug toxicity and toxicity caused by agrochemicals. Mycotoxins, Bacterial toxins. Collections and dispatch of specimens in Toxicological cases, Toxicity of drugs in Aquaculture: Maximum Residual Limits (MRL) of various drugs and chemicals in fish­ Metabolism of toxic substances by aquatic organisms. Endocrine Disrupture Chemicals (EDC)

Detection of heavy metal poisoning. Spot tests for metals. Group reaction for metals- Arsenic, Antimony, Lead (Pb), Mercury (Hg), Zinc (Zn), Barium (Ba), Iron (Fe3+ ), Copper (Cu), Ammonia (ammonium ions) NH4+ Chloride (Cl-), Phosphate (P04) Sulphate (S04 ) Flouride (Fl-), Qualitative detection of Nitrite and Nitrate, Detection of hydrocyanic acid, Detection and Estimation of Mycotoxins, Test for detection of alkaloids, Estimation of LD5O and ED5O Demonstration of drug toxicity.

Suggested Readings-

Fish Pharmacology and Toxicology – Govind Pandey
Fish Pathology -Ronald J. Roberts

Session Plan

Session 1

Theory 1: General Toxicology

PDF link: FT ppt-1

Video link:General toxicology

Session 2

Theory 2: Classification of poison

PDF link: FT ppt-.2

Video link:Classification of poison

Session 3

Theory 3: Toxicity testing

PDF link: FT ppt-3

Video link:Toxicity test

Session 4

Theory 4: Common causes for poisoning

PDF link:Causes of poisoning

Video link:Causes of poisoning

Session 5

Theory 5: Diagnosis of poisoning

PDF link: FT ppt-5

Video link:Diagnosis of poisoning

Session 6

Theory 6: Factors modifying toxicity

PDF link: FT ppt-6

Video link:Factor modifying toxicity

Session 7

Theory 7: Toxicokinetics, Toxicodynamics

PDF link: FT ppt-7

Video link:Toxicokinetics

Session 8

Theory 8: General approaches to diagnosis and treatment of poisoning

PDF link: FT ppt-8

Video link:Treatment of poison animal

Session 9

Theory 9: Systemic Toxicology

PDF link: FT ppt-9

Video link:Systemic toxicity

Session 10

Theory 10: Phytotoxins

PDF link: FT ppt-10

Video link:Phytotoxins

Session 11

Theory 11: Drug toxicity and toxicity caused by agrochemicals

PDF link: FT ppt-11

Video link:Drug toxicity

Session 12

Theory 12: Toxicity caused by Agrochemicals

PDF link: FT ppt-12

Video link:Toxicity caused by Agrochemicals

Session 13

Theory 13: Arsenic & Mercury:  Toxicity effects

PDF link: FT ppt-13

Video link:Arsenic & Mercury: Toxicity effects

Session 14

Theory 14: Bacterial toxins

PDF link: FT ppt-14

Video link:Bacterial toxin

Session 15

Theory 15: EXOTOXINS

PDF link: FT ppt-15

Video link:Mechanism of Exotoxin

Session 16

Theory 16: Collections and dispatch of specimens in Toxicological cases

PDF link: FT ppt-16

Video link:Sample collection

Session 11

Case Studies

Case Studies

Our Main Teachers

Tasok Leya

Assistant professor