Ocular Microbiology and Pathology

Teacher

Mrs. S. Alana Teja

Category

Core Courses

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Course Name : Ocular Microbiology and Pathology

Code(Credit) : CUTM 1789(3-1-0)

CO-PO Mapping

CO’s Description CO-PO

Mapping

CO-1 To understand the insights of general microbiology and pathology PO1 
CO-2 To apply the knowledge in identification of pathogenic diseases of eye PO5,PO10
CO-3 To examine conditions associated with ocular infections PO 7 , PO9 
CO-4 To be able to evaluate systemic diseases of  retina. PO 2 , PO 10

Introduction 

Ocular Microbiology is the study of microorganisms (bacteria, viruses, fungi, and parasites) that infect the eye and its surrounding structures. These microbes can cause conditions such as conjunctivitis, keratitis, endophthalmitis, and uveitis. Understanding the type of pathogen and its mode of infection is essential for effective diagnosis, treatment, and prevention of vision-threatening diseases.

Course Objective:

  •     Equip optometry students with essential knowledge and skills in microbiology and pathology to accurately identify and understand various ocular disorders.
  •     Train technicians to apply correct procedures in laboratory investigations, ensuring accurate interpretation of tests in relation to the underlying pathology.
  • Develop an understanding of the sensitivity, specificity, and limitations of various investigations, enabling technicians to make informed decisions in their practice.

 Course Content

 

Module 1:

 Introduction to Microbiology and Microbial Growth

  •     Introduction to Microbiology

o   Types of Microorganisms

o   Physiology of Microorganisms

  •     Microbial Growth and Control

o   Nutrition, Enzymes, Metabolism, and Energy

o   Microbial Growth

o   Sterilization and Disinfection in the Laboratory

o   Control of Microbial Growth (Antimicrobial Methods and Chemotherapy)

o   Microbes vs. Humans: Infection Development, Disease Process, Pathogenicity, and Virulence

Module 2:

General Pathology and Ocular Infections

  •     General Pathology Principles

o   Pathophysiology of Ocular Angiogenesis

o   Ocular Infections

o   Pathology of Cornea and Conjunctiva

o   Pathology of Uvea and Glaucoma

o   Pathology of Retina

Module 3:

Ocular Bacteriology

  •     Gram-Positive Bacteria

o   Staphylococcus aureus

o   Staphylococcus epidermis

o   Streptococcus

o   Propionic Bacterium

o   Actinomyces

o   Nocardia

  •     Gram-Negative Bacteria

o   Pseudomonas

o   Haemophilus

o   Brucella

o   Neisseria

o   Moraxella

Module 4:

Pathology and Systemic Disease Impact on Eyes

  •     Pathology Related to Systemic Diseases

o   Pathology of Retina in Systemic Diseases/Disorders

o   Pathology of Eyelids and Adnexa

o   Pathology of Orbital Space-Occupying Lesions

  •     Specific Pathologies

o   Pathology of the Optic Nerve

o   Retinoblastoma

o   Pathology of Lens

Module 5:

Microbial and Parasitic Infections Affecting Eyes

  •     Spirochetes and Virology

o   Treponema

o   Leptospiraceae

o   Classification of Viruses in Ocular Disease

o   Rubella, Adenovirus, Oncogenic Viruses (HPV, HBV, EBV, Retroviruses), HIV

  •     Fungi and Parasites

o   Yeasts

o   Filamentous and Dimorphic Fungi

o   Intracellular Parasites (Chlamydia)

o   Protozoa (Toxoplasmosis, Acanthamoeba)

o   Helminths (Toxocariasis, Filariasis, Onchocerciasis, Trematodes)

 

Reference Books:

 

1)    Microbiology: M J Pelczaretal., 1999

 

1)    BURTON G.R.W: Microbiology for the Health Sciences, St. Louis, J.P. Lippincott Co.,3rdEdn.,1988.

2)    Pathology: CORTON KUMAR AND ROBINS (V EDITION) Pathological Basis of the Disease, 2004.

3)    Pathology of the eye & orbit: K S Ratnagar, 1997

4)    MACKIE &Mc CARTNEY Practical Medical Microbiology

5)    SYDNEY M. FINEGOLD & ELLEN JO BARON: Diagnostic Microbiology (DM)

6)    Sherris Medical Microbiology- Editors Kenneth J Ryan /C.George Ray :An Introduction to InfectiousDiseases 4th Edition 2003

7)    CORTON KUMAR AND ROBINS (IV EDITION) : Pathological Basis of the Disease, 1994

8)    S R Lakhani Susan AD & Caroline JF: Basic Pathology: An introduction to the mechanism of disease, 1993.

 Session 1

Introduction to Microbiology and Microbial Growth

Instructor’s PPT https://docs.google.com/presentation/d/1COKTRfyu2pazpLo83IsU6JnmPSKq06iI/edit?slide=id.p1#slide=id.p1

 

Session 2

 Physiology of Microorganisms

Instructor’s PPT https://docs.google.com/presentation/d/1v7GDDBh4u4EDHGq7vDuKuS8LJtG5AbQu/edit?slide=id.p1#slide=id.p1

Session 3, 4, 5

Nutrition, Enzymes, Metabolism, and Energy

Instructor’s PPT https://docs.google.com/presentation/d/1v7GDDBh4u4EDHGq7vDuKuS8LJtG5AbQu/edit?slide=id.p1#slide=id.p1

Session 6, 7

 Microbial Growth

Instructor’s PPT https://docs.google.com/presentation/d/1v7GDDBh4u4EDHGq7vDuKuS8LJtG5AbQu/edit?slide=id.p1#slide=id.p1

  Session 8,9

Sterilization and Disinfection in the Laboratory

Instructor’s PPT https://docs.google.com/presentation/d/1eyTBWYftu5cv8dDP2ZnUdpIKkSYw8TzM/edit?slide=id.p1#slide=id.p1

 Session 10,11

Control of Microbial Growth (Antimicrobial Methods and Chemotherapy)

Instructor’s PPT https://docs.google.com/presentation/d/1v7GDDBh4u4EDHGq7vDuKuS8LJtG5AbQu/edit?slide=id.p1#slide=id.p1

Session 12,13

Pathophysiology of Ocular Angiogenesis

Instructor’s PPThttps://drive.google.com/drive/u/0/folders/1QUSDfwkZddYyuRhF4UlONU2ig4BSVs_D

Session 14, 15

Ocular Infection

Instructor’s PPT https://docs.google.com/presentation/d/1J01bxr4v1_8fwHhbeyUIlOPIwkNh0heS/edit?slide=id.p1#slide=id.p1

Session 16,17

Pathology of Cornea and Conjunctiva

Instructor’s PPT https://docs.google.com/presentation/d/15M6DPxGzkBWimIuFY8P1ogSwyzlkaTMG/edit?slide=id.p1#slide=id.p1

 Session 18,19

Pathology of Uvea and Glaucoma

Instructor’s PPT https://docs.google.com/presentation/d/1dElGwssUNiq-vdLSFyZzMiTpUO_kI1hS/edit?slide=id.p1#slide=id.p1

Session 20

 Pathology of Uvea and Glaucoma

Instructor’s PPT https://docs.google.com/presentation/d/1KlDZY7JZzZd3skaggMYfb3wcr33FwUxe/edit?slide=id.p1#slide=id.p1

Session 21 , 22

  Staphylococcus aureus

Instructor’s PPT https://docs.google.com/presentation/d/1hwr-SGjbeJ58zszuuwZ8F5_qjZRgghd1/edit?slide=id.p1#slide=id.p1

Session 23,24

  Staphylococcus epidermis

Instructor’s PPT https://docs.google.com/presentation/d/1EqHoJxAXco1FuWj-9PYR8ixPoaRaPCT7/edit?slide=id.p1#slide=id.p1

 Session 25,26

Propionic Bacterium

Instructor’s PPThttps://drive.google.com/drive/u/0/folders/1QUSDfwkZddYyuRhF4UlONU2ig4BSVs_D

Session 27,28

Actinomyces

Instructor’s PPT https://drive.google.com/drive/u/0/folders/1QUSDfwkZddYyuRhF4UlONU2ig4BSVs_D

Session 29,30

 Nocardia

Instructor’s PPT https://drive.google.com/drive/u/0/folders/1QUSDfwkZddYyuRhF4UlONU2ig4BSVs_D

session 31

  Pseudomonas,   Haemophilus

Instructor’s PPT https://docs.google.com/presentation/d/1fTf54erSn02ZrKS0OIWjRHqvekRlIC8G/edit?slide=id.p1#slide=id.p1

Session 33,34

Brucella,  Neisseria

Instructor’s PPThttps://docs.google.com/presentation/d/1ECZT7clT9dmwRws_QjCXRATovRRP3yxH/edit?slide=id.p1#slide=id.p1

Session 35,36

Pathology of Retina in Systemic Diseases/Disorders

Instructor’s PPT https://docs.google.com/presentation/d/1TmvjyVOS72EGfOzOhnc5ytQeCMjTeUAl/edit?slide=id.p1#slide=id.p

 Session 37,38

Pathology of Eyelids and Adnexa

Instructor’s PPT https://docs.google.com/presentation/d/1YKLQ20vtK4YRN_gFj98BnA4VTUJgwt_r/edit?slide=id.p1#slide=id.p1

 

Session 39,40

 Pathology of Orbital Space-Occupying Lesions

Instructor’s PPT https://docs.google.com/presentation/d/1nrWYM8d-MRd21NNozDLLDKs_PUUky551/edit?slide=id.p1#slide=id.p1

    Session 41,42

Pathology of Orbital Space-Occupying Lesions

Instructor’s PPT https://docs.google.com/presentation/d/1nrWYM8d-MRd21NNozDLLDKs_PUUky551/edit?slide=id.p1#slide=id.p1

Session 43,44

Helminths (Toxocariasis, Filariasis, Onchocerciasis, Trematodes)

Instructor’s PPT https://docs.google.com/presentation/d/1ZaDgGs-f15Wkz534EC-cS_VDm35zyWg5/edit?slide=id.p1#slide=id.p

Session Plan

Session 12 : 

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