Pharmacology

Teacher

Gulshan Kumar

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Core Courses

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Course Name : Pharmacology

Code(Credit) : FSHM 3103(2-1-0)

Course Objectives

  •  1. Identify the fundamental principles of pharmacokinetics and pharmacodynamics.2. Compare and contrast the specific pharmacology of the major classes of drugs, important distinctions among members of each class, the risks and benefits, in relation to the organ systems they affect, and the diseases for which they are used therapeutically.

Learning Outcomes

  •  Students would have understood the pharmacological actions of different categories of drugs. They would have studied in detailed about mechanism of drug action at organ system/sub cellular/ macromolecular levels. They would have understood the application of basic pharmacological knowledge in the prevention and treatment of various fish diseases.

Course Syllabus

Theory
Introduction to Pharmacology: History, Importance, Terms and Definitions, Drug development, Screening and Nomenclature, Scope of pharmacology in fishes. Route of Administration and Method of application to fish. Source of Drugs.Pharmacolotherapeutic classification of drugs. Pharmacokinetics: Biological membrane, absorption, distribution, biotransformation and Excretion of drugs. Factors influencing drug metabolism. Pharmacodynamics: Principles of drug action, concept of drug receptor, nature, chemistry, classification. Functions of receptor. Transducer mechanism, second messenger, non receptor mediated action. Dose Response Relationship, half life withdrawal period, potency, efficacy, threshold dose, therapeutic dose, maximal dose, toxic dose, lethal dose. Factors modifying drug action, Adverse drug effects, drug interaction and Bioassay of drugs. Salient features in drug acting on digestive system, and reproductive system. Drugs used in fish transporation. Drug resistance. Recent advances in Pharmacology, biostatistics in experimental Pharmacology, Pharmaceutical industry for aqua-medicines.

Practicals
Introduction to Pharmacy, Metrology, Prescription Writing, Preparation of drug solution for fish/shellfishes, Source and chemical nature of drugs, Incompatability, Pharmacutical technology, Bioassay of drugs, Animal models in Pharmacological experiments, Methods of application of drugs in fish/ Aquaculture.

Suggested Readings-

Fish Pharmacology and Toxicology –Govind Pandey
Applied Fish Pharmacology - K.M.T.Brown
Fish Pathology -Ronald J. Roberts

Session Plan

Session 1

Session 1. Theory: Introduction to Pharmacology: History, Importance, Terms and Definitions

Video link

Pharmacology

Session 2

Session 2. Theory: Drug development, Screening and Nomenclature

Session 3

Session 3. Practice: Pharmacology overview/p>

Session 4

Session 4. Theory: Scope of pharmacology in fishes. Route of Administration and Method of application to fish. Source of Drugs.

Video link

Fish pharmacology

Session 5

Session 5. Theory: Pharmacotherapeutic classification of drugs

Video link

Drug classification

Session 6

Session 6. Practice: Nomenclature of organic compound

Session 7

Session 7. Theory: Pharmacokinetics: Biological membrane, absorption, distribution, biotransformation and Excretion of drugs.

Video link

Pharmacokinetics

Session 8

Session 8. Theory: Factors influencing drug metabolism

Video link

Drug metabolism

Session 9

Session 9. Practice: Method of drug application in fish

Video link

Treatment of fish

Session 10

Session 10. Theory: Pharmacodynamics: Principles of drug action, concept of drug receptor, nature, chemistry, classification.

Video link

Pharmacodynamics

Session 11

Session 11. Theory: Functions of receptor. Transducer mechanism, second messenger

Video link

Cell signaling

Session 12

Session 12. Practice: Introduction to pharmacy, metrology and prescription writing

Session 13

Session 13. Theory: Functions of receptor. Transducer mechanism, second messenger

Video link

GPCR signaling

Session 14

Session 14. Theory: non-receptor mediated action of drugs

Session 15

Session 15. Practice: Source and chemical nature of drugs

Session 16

Session 16, Theory: Dose Response Relationship, half life withdrawal period, potency, efficacy

Session 17

Session 17. Theory: Threshold dose, therapeutic dose, maximal dose, toxic dose, lethal dose.

Video link

Therapeutic doses

Session 18

Session 18. Practice: Animal models in pharmacological research

Video link

Animal models

Session 19

Session 19. Theory: Factors modifying drug action

Session 20

Session 20. Theory: Adverse drug effects, drug interaction

Video link

Drug interaction

Session 21

Session 21. Practice: Bioassay of drugs

Video link

Bio-assay

Session 22

Session 22. Theory: Salient features in drug acting on digestive system, and reproductive system.

Session 23

Session 23. Theory: Drugs used in fish transportation

Video link

Fish transport

Session 24

Session 24. Practice: Method of application of drug during fish transportation

Video link

Treatment of fish

Session 25

Session 25. Theory: Drug resistance

Session 26

Session 26. Theory: Recent advances in Pharmacology

Session 27

Session 27. Practice: Introduction to computer added drug design

Session 28

Session 28. Theory: Biostatistics in experimental Pharmacology

Session 29

Session 29. Theory: Pharmaceutical industry for aquamedicines.

Case Studies

Case Studies

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