Pharmacology

Teacher

Dr. Ngairangbam Sushila

Category

Core Courses

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Course Name : Pharmacology

Code(Credit) : FSHM 3103(2-1-0)

Course Objectives

  • Identify the fundamental principles of pharmacokinetics and pharmacodynamics.

  • Compare and contrast the specific pharmacology of the major classes of drugs, important distinctions among members of each class, the risks and benefits, in relation to the organ systems they affect, and the diseases for which they are used therapeutically.

Course Outcome

CO1: Understand the pharmacological actions of different categories of drugs: PO1, PO2

CO2: Study the detailed mechanism of drug action at organ system, sub cellular and macromolecular levels: PO1, PO2

CO3: Understand the application of basic pharmacological knowledge in the prevention and treatment of various fish diseases: PO1,PO2

PO1: Knowledge enhancement: Enhanced knowledge on concepts, essential facts, basics, principles and theories relating to fishery biology, biodiversity and aquatic environment, aquaculture, fish nutrition, fish physiology, genetics and biotechnology, fish processing, fisheries engineering, fish microbiology, fishery extension, economics, and biostatistics.

PO2:Professional and Entrepreneurial Skill development: Understanding the value and processes of life-long learning and professional enhancement and entrepreneurship development.

Course Syllabus

Theory
Introduction to Pharmacology: History, Importance, Terms and Definitions, Drug development, Screening and Nomenclature, Scope of pharmacology in fishes. Route of Administration and Method of application to fish. Source of Drugs.Pharmacolotherapeutic classification of drugs. Pharmacokinetics: Biological membrane, absorption, distribution, biotransformation and Excretion of drugs. Factors influencing drug metabolism. Pharmacodynamics: Principles of drug action, concept of drug receptor, nature, chemistry, classification. Functions of receptor. Transducer mechanism, second messenger, non receptor mediated action. Dose Response Relationship, half life withdrawal period, potency, efficacy, threshold dose, therapeutic dose, maximal dose, toxic dose, lethal dose. Factors modifying drug action, Adverse drug effects, drug interaction and Bioassay of drugs. Salient features in drug acting on digestive system, and reproductive system. Drugs used in fish transporation. Drug resistance. Recent advances in Pharmacology, biostatistics in experimental Pharmacology, Pharmaceutical industry for aqua-medicines.

Practicals
Introduction to Pharmacy, Metrology, Prescription Writing, Preparation of drug solution for fish/shellfishes, Source and chemical nature of drugs, Incompatability, Pharmacutical technology, Bioassay of drugs, Animal models in Pharmacological experiments, Methods of application of drugs in fish/ Aquaculture.

Suggested Readings-

Fish Pharmacology and Toxicology –Govind Pandey
Applied Fish Pharmacology - K.M.T.Brown
Fish Pathology -Ronald J. Roberts

Session Plan

Session 1. Theory: Introduction to Pharmacology: History, Importance, Terms and Definitions

Video link

Pharmacology

Session 2. Theory: Drug development, Screening and Nomenclature

Session 3. Theory: Scope of pharmacology in fishes. Route of Administration and Method of application to fish. Source of Drugs.

Video link

Fish pharmacology

Session 4. Theory: Pharmacotherapeutic classification of drugs

Video link

Drug classification

Session 5. Theory: Pharmacokinetics: Biological membrane, absorption, distribution, biotransformation and Excretion of drugs.

Video link

Pharmacokinetics

Session 6. Theory: Factors influencing drug metabolism

Video link

Drug metabolism

Session 7. Theory: Pharmacodynamics: Principles of drug action, concept of drug receptor, nature, chemistry, classification.

Video link

Pharmacodynamics

Session 8. Theory: Functions of receptor. Transducer mechanism, second messenger

Video link

Cell signaling

Session 9. Theory: Functions of receptor. Transducer mechanism, second messenger

Video link

GPCR signaling

Session 10. Theory: non-receptor mediated action of drugs

Session 11. Theory: Dose Response Relationship, half life withdrawal period, potency, efficacy

Session 12. Theory: Threshold dose, therapeutic dose, maximal dose, toxic dose, lethal dose.

Video link

Therapeutic doses

Session 13. Theory: Factors modifying drug action

Session 14. Theory: Adverse drug effects, drug interaction

Video link

Drug interaction

Session 15. Theory: Salient features in drug acting on digestive system, and reproductive system.

Session 16. Theory: Drugs used in fish transportation

Video link

Fish transport

Session 17. Theory: Drug resistance

Session 18. Theory: Recent advances in Pharmacology

Session 19. Theory: Biostatistics in experimental Pharmacology

Session 20. Theory: Pharmaceutical industry for aquamedicines.

Session 21. Practice: Introduction to pharmacy, metrology and prescription writing

Session 22. Practice: Source and chemical nature of drugs

Session 23. Practice: Animal models in pharmacological research

Video link

Animal models

Session 24. Practice: Bioassay of drugs

Video link

Bio-assay

Session 25. Practice: Method of application of drug during fish transportation

Video link

Treatment of fish

Session 26. Practice: Introduction to computer added drug design

Session 27. Practice: Method of drug application in fish

Video link

Treatment of fish

Model Questions

Model-QB_Pharmacology

Our Main Teachers

Dr. Ngairangbam Sushila joined the University as an Assistant Professor in the department of Aquatic Animal  Health Management, School of Fisheries. She completed her doctoral programme from ICAR-Central Institute of Fisheries Education, Mumbai.

Gulshan Kumar

Asst Professor,SOF
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