PHYSICAL PHARMACEUTICS-I (PRACTICAL)

Teacher

Dr. Rasmita Dash

Category

Core Courses

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Course Name: Physical Pharmaceutics-1 (Practical)

Code(Credit):BP306P(0-2-0)

Course Objectives

The objectives of the course are

  • Demonstrate the ability to perform solubility determination experiments at room temperature accurately and safely, following established laboratory protocols.
  • Practical components of the subject help the student to get a better insight into various areas of formulation research and development.
  • Ability to solve practical challenges in pharmaceutical product development and quality control.

Course Syllabus

  1. Determination the solubility of drug at room temperature.
  1. Determination of pKa value by Half Neutralization/ Henderson Hasselbalch equation.
  1. Determination of Partition co- efficient of benzoic acid in benzene and water.
  2. Determination of Partition co- efficient of Iodine in CCl4 and water.
  3. Determination of % composition of NaCl in a solution using phenol-water system by CST method.
  4. Determination of surface tension of given liquids by drop weight method.
  5. Determination of surface tension of given liquids by drop count method.
  6. Determination of HLB number of a surfactant by saponification method.
  7. Determination of Freundlich and Langmuir constants using activated char coal.
  8. Determination of critical micellar concentration of surfactants.

 

Learning Outcomes

Apply solubility and partitioning techniques for drug analysis.

Discover drug pKa using neutralization methods.

Classify liquids by surface tension.

Prepare stability constants for drug complexes.

Model surfactant properties through HLB and micellar concentration.

Session Plan

Our Main Teachers

Dr. Rasmita Dash

Assistant Professor
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Dr. Rasmita Dash holds a Master of Pharmacy (M.Pharm) and a Doctor of Philosophy (Ph.D.) in Pharmaceutical Sciences. Her academic and research pursuits are centered around innovative approaches in drug delivery and design. With a strong foundation in pharmaceutics, her core areas of expertise include Novel Drug Delivery Systems (NDDS), Nanoparticulate Drug Delivery Systems, and […]