Optical isomerism –
Optical activity, enantiomerism, diastereoisomerism, meso compounds
Elements of symmetry, chiral and achiral molecules
DL system of nomenclature of optical isomers, sequence rules, RS system of
nomenclature of optical isomers
Reactions of chiral molecules
Racemic modification and resolution of racemic mixture.
Asymmetric synthesis: partial and absolute
Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems)
Methods of determination of configuration of geometrical isomers.
Conformational isomerism in Ethane, n-Butane and Cyclohexane.
Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for optical
Stereospecific and stereoselective reactions
Nomenclature and classification
Synthesis, reactions and medicinal uses of following compounds/derivatives Pyrrole,
Furan, and Thiophene
Relative aromaticity and reactivity of Pyrrole, Furan and Thiophene
Synthesis, reactions and medicinal uses of following compounds/derivatives Pyrazole,
Imidazole, Oxazole and Thiazole. Pyridine, Quinoline, Isoquinoline, Acridine and
Indole. Basicity of pyridine, Synthesis and medicinal uses of Pyrimidine, Purine,
azepines and their derivatives
Reactions of synthetic importance
Metal hydride reduction (NaBH4 and LiAlH4), Clemmensen reduction, Birch
reduction, Wolff Kishner reduction.
Oppenauer-oxidation and Dakin reaction.
Beckmanns rearrangement and Schmidt rearrangement.
1. Organic chemistry by I.L. Finar, Volume-I & II.
2. A text book of organic chemistry – Arun Bahl, B.S. Bahl.
3. Heterocyclic Chemistry by Raj K. Bansal
4. Organic Chemistry byMorrison and Boyd