Dr Fahima Dilnawaz

Objective
  • To provide depth knowledge of biological or medicinal processes through the investigation of the underlying molecular mechanisms.
• Understanding of chemical and molecular processes that occur in and between cells.   •Understanding will become such that, can be able to describe and explain processes and their meaning for the characteristics of living organisms. Learning outcome To gain complete knowledge of the physiological activity of the cells in molecular level  
COs Course outcomes Mapping COs with POs (High-3, Medium-2, Low-1)
CO1 Understand the detailed functions of the cells and knowledge of intricate molecular networks and functions, PO1 (3)
CO2 Identification of a problem, review of the literature and analyze its molecular problems and to design, as well as conduct experiments, analysis and interpretation of data PO2 (3):
CO3, CO4 Students will function effectively as an individual, and as a member or leaders in diverse teams, and in multidisciplinary settings of molecular biology PO9 (3):
CO5 Use of research-based knowledge  and research methodology for experiments, analysis, and interpretation of data, in molecular biology PO2 (3)
Course content  Module I: Introduction to molecular biology (4hrs) Introduction to molecular biology, Evolution and Molecular structure of cell and its organelles.Types of cells. Including different kinds of Prokaryotic and eukaryotic cells. https://www.youtube.com/watch?v=VDnuSmc4hEA (Evolution of Cell) https://www.youtube.com/watch?v=RQ-SMCmWB1s (Prokaryotic and eukaryotic cells) https://www.youtube.com/watch?v=IA0DhWDTUpU (Cell Organelles) https://www.youtube.com/watch?v=bWaXJfyXfCQ (Structural form of DNA) Module II: Molecular Biology Of cell (4hrs) Cell growth, Cell adhesion, cell junctions and extra cellular matrix organelles, Cell cycle, Cell membrane and its structure (fluid-mosaic model). Factors influencing on membrane fluidity, asymmetry of membrane and membrane transport (active and passive) https://www.youtube.com/watch?v=CNbZDcibegY (Fluid mosaic model) https://www.youtube.com/watch?v=e6N9_RhD10Q (Cell cycle) www.youtube.com/watch?v=5bq1To_RKEo (M Phase of cell cycle) https://www.youtube.com/watch?v=VLJF8Pf8spw (cell cycle regulators)  Module III: Molecular Nature of the Genetic Material (4hrs) Molecular Nature of the Genetic Material in Prokaryotic and Eukaryotic Cells:Molecular biology of Genes, DNA: Molecular structure, types: Primary, secondary and tertiary, Double helix, types,  Transferring information from DNA to RNA, Synthesis of RNA, TranslationRNA: Molecular structure, types. Evolution of DNA and RNA, Gene and genetic codes https://www.youtube.com/watch?v=ftyM-LcELSI (genes and genetic code) https://www.youtube.com/watch?v=QcBYTA7uVXk (Translation) https://www.youtube.com/watch?v=ftyM-LcELSI (genes and genetic code) Module IV: Regulation of the Gene Expression (4hrs) General Concept on Regulation of the Gene Expression, Regulating the Metabolism:The Lac- Operon system, Catabolic repression, Trp Operon system: regulating the biosynthesis of the tryptophan, Gene expression in Eukaryotic cells, Plasmids: types, maintenance and functions. https://www.youtube.com/watch?v=XspyeURhrcQ (Trp regulation) https://www.youtube.com/watch?v=0jCOGuDcUXg (gene expression in eukaryotes) https://www.youtube.com/watch?v=EjRXz1xAdow (Lac operon) Module V: DNA Replication and Gene Expression (5hrs) DNA Replication and Gene Expression: DNA Replication: Semi conservative Nature of DNA Replication, DNA Replication in prokaryotic Cells, DNA Replication in Eukaryotic cell, Enzymes involved in DNA Replication: DNA polymerases, Proofreading, post-replication Modification of DNA. https://www.youtube.com/watch?v=2_-jSoSaaTA (DNA replication) https://www.youtube.com/watch?v=T1aR77FLdi0 (Semiconservative DNA replication) https://www.youtube.com/watch?v=IjVLhoyfGAM (DNA replication in prokaryotes) https://www.youtube.com/watch?v=KSlmkkN5ipE (DNA replication in eukaryotes) Module VI: Transcription(5hrs) Transferring information from DNA to RNA, Synthesis of RNA(Transcription), RNA polymerase, Initiation and Termination of Transcription, Post and co- transcription modification of the RNA https://www.youtube.com/watch?v=gG7uCskUOrA (Transcription)    Module VII : Translation (4hrs) Protein Biosynthesis: Translation of the genetic code,Translation of m RNA,Role of r-RNA in protein synthesis, Forming the polypeptides- elongation,Termination of the protein biosynthesis. https://www.youtube.com/watch?v=QcBYTA7uVXk (Translation) Practice:
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Animal Biotechnology-CUTM2365, Credits (3-0-1)

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Cell Biology-CUTM 1124, (Credit-4) T(3)-P (0)-Pj (1)

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Molecular Biology (CUTM1125),3-0-1

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