Physical Pharmaceutics- II (Practical)

Teacher

Yashwant Giri

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Course Name: Physical Pharmaceutics-II

Course Code: BPHL2202(0-2-0)

Course Objectives:

The course deals with the various physical and physicochemical properties, and principles involved in dosage forms/formulations. Practical components of the subject help the student to get a better insight into various areas of formulation research and development, and stability studies of  pharmaceutical dosage forms.

Course Outcome:

CO OUTCOMES PO MAPPING
CO1 Upon the completion of the course student shall be able to:

Dispersions

 

PO1
CO2 Understand various physicochemical properties of drug molecules in the designing the dosage form PO1,PO,PO3
CO3 Know the principles of chemical kinetics & to use them in assigning expiry date for formulation PO1,PO11
CO4 Demonstrate use of physicochemical properties in evaluation of dosage forms. PO1,PO5
CO5 Appreciate physicochemical properties of drug molecules in formulation research and development. PO1,PO2,PO3

Syllabus:

1. Determination of particle size, particle size distribution using sieving method
2. Determination of particle size, particle size distribution using Microscopic method
3. Determination of bulk density, true density and porosity
4. Determine the angle of repose and influence of lubricant on angle of repose
5. Determination of viscosity of liquid using Ostwald’s viscometer
6. Determination sedimentation volume with effect of different suspending agent
7. Determination sedimentation volume with effect of different concentration of single suspending agent
8. Determination of viscosity of semisolid by using Brookfield viscometer
9. Determination of reaction rate constant first order.

10. Determination of reaction rate constant second order
11. Accelerated stability studies

Session Plan:

EXPERIMENT 1

Determination of particle size, particle size distribution using sieving method

https://www.youtube.com/watch?v=kySbeE3dKx4

PP-II EXPERIMENT -1 particle size sieving methods

EXPERIMENT 2

Determination of particle size, particle size distribution using Microscopic method

https://www.youtube.com/watch?v=I3Gc5MvExOk&t=102s

PP-II EXPERIMENT-2 particle size microscopic methods

EXPERIMENT 3

Determination of bulk density, true density and porosity

https://www.youtube.com/watch?v=OwgxgjZ_wis&t=49s

PP-II EXPERIMENT - 3 bulk density

EXPERIMENT 4

Determine the angle of repose and influence of lubricant on angle of repose

https://www.youtube.com/watch?v=rPCOUitcOV4&t=82s

PP-II EXPERIMENT -4 angle of repose

EXPERIMENT 5

Determination of viscosity of liquid using Ostwald’s viscometer

https://www.youtube.com/watch?v=68bo-h3Kf7s&t=43s

PP -II EXPERIMENT -5 viscosity

EXPERIMENT 6

Determination sedimentation volume with effect of different suspending agent

https://www.youtube.com/watch?v=Cg5HZcxTt0M&t=74s

PP-II EXPERIMENT -6 sedimentation volume with single suspending agent

EXPERIMENT 7

Determination sedimentation volume with effect of different concentration of single suspending agent

PP -II EXPERIMENT -7 sedimentation volume with multiple suspending agent

https://www.youtube.com/watch?v=jxS1QEE9BSk&t=12s

EXPERIMENT 8

Determination of viscosity of semisolid by using Brookfield viscometer

https://www.youtube.com/watch?v=KUZ67eCYzVY&t=38s

PP-II EXPERIMENT -8 brookfield viscometer

EXPERIMENT 9

Determination of reaction rate constant first order

https://www.youtube.com/watch?v=kPONd5Wo-Yg

PP-II EXPERIMENT -9 reaction rate constant 1st order

EXPERIMENT 10

Determination of reaction rate constant second order

https://www.youtube.com/watch?v=k16cvTtp2aw&t=32s

PP-II EXPERIMENT -10 2nd

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Yashwant Giri

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